Inhibition of dipeptidyl peptidase-4 ameliorates cardiac ischemia and systolic dysfunction by up-regulating the FGF-2/EGR-1 pathway

• Masayoshi Suda ,

  Contributed equally to this work with: Masayoshi Suda, Ippei Shimizu

  Roles Investigation, Writing – original draft

  Affiliation Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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• Ippei Shimizu ,

  Contributed equally to this work with: Masayoshi Suda, Ippei Shimizu

  Roles Conceptualization, Funding acquisition, Writing – original draft

  Affiliations Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan, Division of Molecular Aging and Cell Biology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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• Yohko Yoshida,

  Roles Funding acquisition, Investigation

  Affiliations Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan, Division of Molecular Aging and Cell Biology, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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• Yuka Hayashi,

  Roles Investigation

  Affiliation Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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• Ryutaro Ikegami,

  Roles Investigation

  Affiliation Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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• Goro Katsuumi,

  Roles Investigation

  Affiliation Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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• Takayuki Wakasugi,

  Roles Investigation

  Affiliation Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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• Yutaka Yoshida,

  Roles Formal analysis

  Affiliation Department of Structural Pathology, Institute of Nephrology, Graduate School of Medical and Dental Sciences, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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• Shujiro Okuda,

  Roles Formal analysis

  Affiliation Division of Bioinformatics, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

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• Tomoyoshi Soga,

  Roles Resources

  Affiliation Institute for Advanced Biosciences, Keio University, Yamagata, Japan

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• Tohru Minamino

  Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

  * E-mail: tminamino@med.niigata-u.ac.jp

  Affiliation Department of Cardiovascular Biology and Medicine, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan

  http://orcid.org/0000-0003-1627-6151

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