Histone deacetylase inhibition prevents cell death induced by loss of tricellular tight junction proteins in temperature-sensitive mouse cochlear cells

Kenichi Takano; Takuya Kakuki; Yakuto Kaneko; Takayuki Kohno; Shin Kikuchi; Tetsuo Himi; Takashi Kojima

doi:10.1371/journal.pone.0182291

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Open Access

Peer-reviewed

Research Article

Histone deacetylase inhibition prevents cell death induced by loss of tricellular tight junction proteins in temperature-sensitive mouse cochlear cells

Kenichi Takano ,

Contributed equally to this work with: Kenichi Takano, Takuya Kakuki

Roles Conceptualization, Funding acquisition, Investigation, Supervision, Writing – original draft

* E-mail: ktakashi@sapmed.ac.jp

Affiliation Department of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo, Japan

http://orcid.org/0000-0001-8706-6384

⨯
Takuya Kakuki ,

Contributed equally to this work with: Kenichi Takano, Takuya Kakuki

Roles Data curation, Investigation, Resources

Affiliations Department of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo, Japan, Department of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Yakuto Kaneko,

Roles Investigation, Resources

Affiliations Department of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo, Japan, Department of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Takayuki Kohno,

Roles Investigation, Resources

Affiliation Department of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Shin Kikuchi,

Roles Investigation

Affiliation Department of Anatomy, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Tetsuo Himi,

Roles Conceptualization, Project administration, Supervision

Affiliation Department of Otolaryngology, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯
Takashi Kojima

Roles Conceptualization, Data curation, Funding acquisition, Investigation, Project administration, Resources, Supervision, Writing – review & editing

Affiliation Department of Cell Science, Research Institute for Frontier Medicine, Sapporo Medical University School of Medicine, Sapporo, Japan
⨯

Histone deacetylase inhibition prevents cell death induced by loss of tricellular tight junction proteins in temperature-sensitive mouse cochlear cells

Kenichi Takano,
Takuya Kakuki,
Yakuto Kaneko,
Takayuki Kohno,
Shin Kikuchi,
Tetsuo Himi,
Takashi Kojima

Published: August 2, 2017
https://doi.org/10.1371/journal.pone.0182291

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