Glutamate alleviates muscle protein loss by modulating TLR4, NODs, Akt/FOXO and mTOR signaling pathways in LPS-challenged piglets

Ping Kang; Xiuying Wang; Huanting Wu; Huiling Zhu; Yongqing Hou; Longmei Wang; Yulan Liu

doi:10.1371/journal.pone.0182246

Loading metrics

Open Access

Peer-reviewed

Research Article

Glutamate alleviates muscle protein loss by modulating TLR4, NODs, Akt/FOXO and mTOR signaling pathways in LPS-challenged piglets

Ping Kang,

Roles Data curation, Formal analysis, Methodology, Project administration, Writing – original draft, Writing – review & editing

Affiliation Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, People’s Republic of China
⨯
Xiuying Wang,

Roles Data curation, Formal analysis, Methodology

Affiliation Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, People’s Republic of China
⨯
Huanting Wu,

Roles Methodology, Project administration

Affiliation Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, People’s Republic of China
⨯
Huiling Zhu,

Roles Methodology

Affiliation Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, People’s Republic of China
⨯
Yongqing Hou,

Roles Conceptualization, Project administration, Supervision

Affiliation Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, People’s Republic of China
⨯
Longmei Wang,

Roles Methodology

Affiliation Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, People’s Republic of China
⨯
Yulan Liu

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

* E-mail: yulanflower@126.com

Affiliation Hubei Collaborative Innovation Center for Animal Nutrition and Feed Safety, Hubei Key Laboratory of Animal Nutrition and Feed Science, Wuhan Polytechnic University, Wuhan, People’s Republic of China

http://orcid.org/0000-0003-3320-2381

⨯

Glutamate alleviates muscle protein loss by modulating TLR4, NODs, Akt/FOXO and mTOR signaling pathways in LPS-challenged piglets

Ping Kang,
Xiuying Wang,
Huanting Wu,
Huiling Zhu,
Yongqing Hou,
Longmei Wang,
Yulan Liu

Published: August 4, 2017
https://doi.org/10.1371/journal.pone.0182246

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Gastrocnemius muscles
Is the Subject Area "Gastrocnemius muscles" applicable to this article?

Thanks for your feedback.
Muscle proteins
Is the Subject Area "Muscle proteins" applicable to this article?

Thanks for your feedback.
Swine
Is the Subject Area "Swine" applicable to this article?

Thanks for your feedback.
Diet
Is the Subject Area "Diet" applicable to this article?

Thanks for your feedback.
Toll-like receptors
Is the Subject Area "Toll-like receptors" applicable to this article?

Thanks for your feedback.
Glutamate
Is the Subject Area "Glutamate" applicable to this article?

Thanks for your feedback.
Immune receptor signaling
Is the Subject Area "Immune receptor signaling" applicable to this article?

Thanks for your feedback.
Skeletal muscles
Is the Subject Area "Skeletal muscles" applicable to this article?

Thanks for your feedback.