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Open Access
Peer-reviewed
Research Article
YM155 as an inhibitor of cancer stemness simultaneously inhibits autophosphorylation of epidermal growth factor receptor and G9a-mediated stemness in lung cancer cells
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Chun-Chia Cheng,
Roles Data curation, Formal analysis, Investigation, Methodology, Writing – original draft
Affiliations Division of Hematology and Oncology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan, Laboratory of Good Clinical Research Center, Department of Medical Research, MacKay Memorial Hospital, Tamsui District, New Taipei City, Taiwan, Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
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Jungshan Chang,
Roles Conceptualization
Affiliation Graduate Institute of Medical Sciences, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
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Stanley Ching-Cheng Huang,
Roles Writing – review & editing
Affiliation Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, Missouri, United States of America
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Huan-Chau Lin,
Roles Funding acquisition
Affiliations Division of Hematology and Oncology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan, Laboratory of Good Clinical Research Center, Department of Medical Research, MacKay Memorial Hospital, Tamsui District, New Taipei City, Taiwan
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Ai-Sheng Ho,
Roles Conceptualization, Funding acquisition
Affiliation Division of Gastroenterology, Cheng Hsin General Hospital, Taipei, Taiwan
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Ken-Hong Lim,
Roles Conceptualization, Supervision
Affiliations Division of Hematology and Oncology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan, Laboratory of Good Clinical Research Center, Department of Medical Research, MacKay Memorial Hospital, Tamsui District, New Taipei City, Taiwan
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Chun-Chao Chang,
Roles Conceptualization, Data curation, Resources
Affiliations Division of Gastroenterology and Hepatology, Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan, Division of Gastroenterology and Hepatology, Department of Internal Medicine, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan
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Ling Huang,
Roles Writing – review & editing
Affiliations Division of Hematology and Oncology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan, Laboratory of Good Clinical Research Center, Department of Medical Research, MacKay Memorial Hospital, Tamsui District, New Taipei City, Taiwan
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Yu-Cheng Chang,
Roles Validation
Affiliations Division of Hematology and Oncology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan, Laboratory of Good Clinical Research Center, Department of Medical Research, MacKay Memorial Hospital, Tamsui District, New Taipei City, Taiwan
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Yi-Fang Chang ,
Roles Conceptualization, Project administration, Supervision, Writing – review & editing
* E-mail: changyifang@gmail.com (YF Chang); ken@ibms.sinica.edu.tw (CW Wu)
Affiliations Division of Hematology and Oncology, Department of Internal Medicine, MacKay Memorial Hospital, Taipei, Taiwan, Laboratory of Good Clinical Research Center, Department of Medical Research, MacKay Memorial Hospital, Tamsui District, New Taipei City, Taiwan
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Cheng-Wen Wu
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing
* E-mail: changyifang@gmail.com (YF Chang); ken@ibms.sinica.edu.tw (CW Wu)
Affiliation Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan
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YM155 as an inhibitor of cancer stemness simultaneously inhibits autophosphorylation of epidermal growth factor receptor and G9a-mediated stemness in lung cancer cells
- Chun-Chia Cheng,
- Jungshan Chang,
- Stanley Ching-Cheng Huang,
- Huan-Chau Lin,
- Ai-Sheng Ho,
- Ken-Hong Lim,
- Chun-Chao Chang,
- Ling Huang,
- Yu-Cheng Chang,
- Yi-Fang Chang
- Published: August 7, 2017
- https://doi.org/10.1371/journal.pone.0182149