Imidazoquinoxaline anticancer derivatives and imiquimod interact with tubulin: Characterization of molecular microtubule inhibiting mechanisms in correlation with cytotoxicity

• Alexis Courbet ,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: acourbet@uw.edu (AC); florence.gattacceca@umontpellier.fr (FG)

  Affiliations University of Montpellier, Montpellier, France, Department of Biochemistry & Institute for Protein Design, University of Washington, Seattle, WA, United States of America

  http://orcid.org/0000-0003-0539-7011

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• Nicole Bec,

  Roles Investigation, Methodology

  Affiliations University of Montpellier, Montpellier, France, IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, IRCM, Institut de Recherche en Cancérologie de Montpellier INSERM U1194, Montpellier, France, Institut Régional du Cancer de Montpellier, Montpellier, France

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• Caroline Constant,

  Roles Methodology, Validation, Visualization

  Affiliation IRCM, Institut de Recherche en Cancérologie de Montpellier INSERM U1194, Montpellier, France

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• Christian Larroque,

  Roles Conceptualization, Investigation, Methodology, Resources, Supervision, Validation

  Affiliations University of Montpellier, Montpellier, France, IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, IRCM, Institut de Recherche en Cancérologie de Montpellier INSERM U1194, Montpellier, France, Institut Régional du Cancer de Montpellier, Montpellier, France

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• Martine Pugniere,

  Roles Data curation, Formal analysis, Methodology, Resources, Validation

  Affiliations University of Montpellier, Montpellier, France, IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, IRCM, Institut de Recherche en Cancérologie de Montpellier INSERM U1194, Montpellier, France, Institut Régional du Cancer de Montpellier, Montpellier, France

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• Safia El Messaoudi,

  Roles Data curation, Formal analysis

  Affiliations University of Montpellier, Montpellier, France, IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, IRCM, Institut de Recherche en Cancérologie de Montpellier INSERM U1194, Montpellier, France, Institut Régional du Cancer de Montpellier, Montpellier, France

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• Zahraa Zghaib,

  Roles Data curation, Formal analysis

  Affiliation IBMM, Institut des Biomolécules Max Mousseron, UMR 5247, Université de Montpellier, Montpellier, France

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• Sonia Khier,

  Roles Conceptualization, Funding acquisition, Investigation, Validation

  Affiliations University of Montpellier, Montpellier, France, IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, IRCM, Institut de Recherche en Cancérologie de Montpellier INSERM U1194, Montpellier, France, Institut Régional du Cancer de Montpellier, Montpellier, France

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• Carine Deleuze-Masquefa,

  Roles Conceptualization, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation

  Affiliation IBMM, Institut des Biomolécules Max Mousseron, UMR 5247, Université de Montpellier, Montpellier, France

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• Florence Gattacceca

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: acourbet@uw.edu (AC); florence.gattacceca@umontpellier.fr (FG)

  Affiliations University of Montpellier, Montpellier, France, IRCM, Institut de Recherche en Cancérologie de Montpellier, Montpellier, France, IRCM, Institut de Recherche en Cancérologie de Montpellier INSERM U1194, Montpellier, France, Institut Régional du Cancer de Montpellier, Montpellier, France

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