Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors

• Weimei Xing ,

  Contributed equally to this work with: Weimei Xing, Ona Barauskas

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Writing – original draft, Writing – review & editing

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

  http://orcid.org/0000-0002-8645-8850

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• Ona Barauskas ,

  Contributed equally to this work with: Weimei Xing, Ona Barauskas

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Writing – original draft, Writing – review & editing

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Thorsten Kirschberg,

  Roles Data curation, Methodology, Resources

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Anita Niedziela-Majka,

  Roles Data curation, Methodology, Resources, Validation, Writing – review & editing

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Michael Clarke,

  Roles Conceptualization, Investigation, Resources

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Gabriel Birkus,

  Roles Data curation, Methodology, Validation

  Current address: Institute of Organic Chemistry and Biochemistry, Flemingovo nam 2, Prague 6, Czech Republic

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Perry Weissburg,

  Roles Data curation, Methodology, Validation

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Xiaohong Liu,

  Roles Resources, Supervision

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Brian E. Schultz,

  Roles Conceptualization, Investigation, Resources, Supervision, Writing – review & editing

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Roman Sakowicz,

  Roles Investigation, Project administration, Supervision, Writing – review & editing

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• HyockJoo Kwon ,

  Roles Conceptualization, Investigation, Resources, Supervision, Writing – review & editing

  * E-mail: HyockJoo.Kwon@gilead.com (HJK); Joy.Feng@gilead.com (JYF)

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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• Joy Y. Feng

  Roles Conceptualization, Investigation, Resources, Supervision, Writing – review & editing

  * E-mail: HyockJoo.Kwon@gilead.com (HJK); Joy.Feng@gilead.com (JYF)

  Affiliation Gilead Sciences, Inc., Foster City, California, United States of America

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