Targeted next-generation sequencing detects novel gene–phenotype associations and expands the mutational spectrum in cardiomyopathies

• Cinzia Forleo ,

  Contributed equally to this work with: Cinzia Forleo, Anna Maria D’Erchia, Sandro Sorrentino

  Roles Conceptualization, Data curation, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: cinzia.forleo@uniba.it (CF); annamaria.derchia@uniba.it (AMD)

  ¶‡ CF, AMD, and SS contributed equally to this work as co-first authors. GP and SF contributed equally to this work as joint senior authors.

  Affiliation Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy

  http://orcid.org/0000-0002-9452-4037

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• Anna Maria D’Erchia ,

  Contributed equally to this work with: Cinzia Forleo, Anna Maria D’Erchia, Sandro Sorrentino

  Roles Conceptualization, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: cinzia.forleo@uniba.it (CF); annamaria.derchia@uniba.it (AMD)

  ¶‡ CF, AMD, and SS contributed equally to this work as co-first authors. GP and SF contributed equally to this work as joint senior authors.

  Affiliations Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari Aldo Moro, Bari, Italy, Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), National Research Council, Bari, Italy

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• Sandro Sorrentino ,

  Contributed equally to this work with: Cinzia Forleo, Anna Maria D’Erchia, Sandro Sorrentino

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  ¶‡ CF, AMD, and SS contributed equally to this work as co-first authors. GP and SF contributed equally to this work as joint senior authors.

  Affiliation Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy

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• Caterina Manzari,

  Roles Formal analysis, Investigation, Resources, Validation, Visualization, Writing – original draft

  Affiliation Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), National Research Council, Bari, Italy

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• Matteo Chiara,

  Roles Formal analysis, Investigation, Resources

  Affiliation Department of Biosciences, University of Milano, Milano, Italy

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• Massimo Iacoviello,

  Roles Data curation, Investigation, Resources

  Affiliation Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy

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• Andrea Igoren Guaricci,

  Roles Data curation, Investigation, Resources

  Affiliation Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy

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• Delia De Santis,

  Roles Data curation, Investigation, Resources

  Affiliation Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy

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• Rita Leonarda Musci,

  Roles Data curation, Investigation, Resources

  Affiliation Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy

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• Antonino La Spada,

  Roles Data curation, Investigation, Resources

  Affiliation Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy

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• Vito Marangelli,

  Roles Data curation, Investigation, Resources

  Affiliation Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy

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• Graziano Pesole ,

  Roles Conceptualization, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  ¶‡ CF, AMD, and SS contributed equally to this work as co-first authors. GP and SF contributed equally to this work as joint senior authors.

  Affiliations Department of Biosciences, Biotechnology and Biopharmaceutics, University of Bari Aldo Moro, Bari, Italy, Institute of Biomembranes, Bioenergetics and Molecular Biotechnologies (IBIOM), National Research Council, Bari, Italy

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• Stefano Favale

  Roles Conceptualization, Data curation, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

  ¶‡ CF, AMD, and SS contributed equally to this work as co-first authors. GP and SF contributed equally to this work as joint senior authors.

  Affiliation Cardiology Unit, Department of Emergency and Organ Transplantation, University of Bari Aldo Moro, Bari, Italy

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