Probing the compartmentalization of HIV-1 in the central nervous system through its neutralization properties

Karl Stefic; Antoine Chaillon; Mélanie Bouvin-Pley; Alain Moreau; Martine Braibant; Frédéric Bastides; Guillaume Gras; Louis Bernard; Francis Barin

doi:10.1371/journal.pone.0181680

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Open Access

Peer-reviewed

Research Article

Probing the compartmentalization of HIV-1 in the central nervous system through its neutralization properties

Karl Stefic,

Roles Conceptualization, Formal analysis, Investigation, Writing – original draft

Affiliations Université François Rabelais, Inserm U966, Tours, France, Laboratoire de Bactériologie-Virologie, CHU Bretonneau, Tours, France

http://orcid.org/0000-0002-9686-9194

⨯
Antoine Chaillon,

Roles Conceptualization, Formal analysis, Methodology, Supervision, Validation, Writing – original draft

Affiliation Deparment of Medicine, University of California San Diego, La Jolla, California, United States of America
⨯
Mélanie Bouvin-Pley,

Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

Affiliation Université François Rabelais, Inserm U966, Tours, France

http://orcid.org/0000-0002-2480-931X

⨯
Alain Moreau,

Roles Conceptualization, Formal analysis, Methodology, Writing – review & editing

Affiliation Université François Rabelais, Inserm U966, Tours, France
⨯
Martine Braibant,

Roles Conceptualization, Methodology, Supervision, Writing – review & editing

Affiliation Université François Rabelais, Inserm U966, Tours, France
⨯
Frédéric Bastides,

Roles Investigation, Validation, Writing – review & editing

Affiliation Médecine Interne et Maladies Infectieuses, CHU Bretonneau, Tours, France
⨯
Guillaume Gras,

Roles Investigation, Validation, Writing – review & editing

Affiliation Médecine Interne et Maladies Infectieuses, CHU Bretonneau, Tours, France

http://orcid.org/0000-0002-6136-5869

⨯
Louis Bernard,

Roles Investigation, Validation, Writing – review & editing

Affiliation Médecine Interne et Maladies Infectieuses, CHU Bretonneau, Tours, France
⨯
Francis Barin

Roles Conceptualization, Formal analysis, Methodology, Supervision, Writing – original draft

* E-mail: francis.barin@univ-tours.fr

Affiliations Université François Rabelais, Inserm U966, Tours, France, Laboratoire de Bactériologie-Virologie, CHU Bretonneau, Tours, France
⨯

Probing the compartmentalization of HIV-1 in the central nervous system through its neutralization properties

Karl Stefic,
Antoine Chaillon,
Mélanie Bouvin-Pley,
Alain Moreau,
Martine Braibant,
Frédéric Bastides,
Guillaume Gras,
Louis Bernard,
Francis Barin

Published: August 25, 2017
https://doi.org/10.1371/journal.pone.0181680

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Cerebrospinal fluid
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Blood plasma
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Central nervous system
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HIV-1
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Blood
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Viral evolution
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Antiretroviral therapy
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Antibodies
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