Development and clinical testing of individual immunoassays for the quantification of serum glycoproteins to diagnose prostate cancer

Kathrin Endt; Jens Goepfert; Aurelius Omlin; Alcibiade Athanasiou; Pierre Tennstedt; Anna Guenther; Maurizio Rainisio; Daniel S. Engeler; Thomas Steuber; Silke Gillessen; Thomas Joos; Ralph Schiess

doi:10.1371/journal.pone.0181557

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Open Access

Peer-reviewed

Research Article

Development and clinical testing of individual immunoassays for the quantification of serum glycoproteins to diagnose prostate cancer

Kathrin Endt,

Roles Data curation, Investigation, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

Affiliation ProteoMediX Inc., Schlieren, Switzerland
⨯
Jens Goepfert,

Roles Data curation, Investigation, Methodology, Project administration, Supervision, Writing – review & editing

Affiliation NMI Tübingen, Reutlingen, Germany
⨯
Aurelius Omlin,

Roles Data curation, Writing – review & editing

Affiliation Cantonal Hospital St. Gallen, St. Gallen, Switzerland
⨯
Alcibiade Athanasiou,

Roles Formal analysis, Visualization

Affiliation ProteoMediX Inc., Schlieren, Switzerland
⨯
Pierre Tennstedt,

Roles Data curation, Formal analysis, Software, Visualization, Writing – review & editing

Affiliation Martini-Klinik, Hamburg-Eppendorf, Germany
⨯
Anna Guenther,

Roles Formal analysis

Affiliation NMI Tübingen, Reutlingen, Germany
⨯
Maurizio Rainisio,

Roles Software

Affiliation Abanovus LLC, Sanremo, Italy
⨯
Daniel S. Engeler,

Roles Data curation, Writing – review & editing

Affiliation Cantonal Hospital St. Gallen, St. Gallen, Switzerland
⨯
Thomas Steuber,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Martini-Klinik, Hamburg-Eppendorf, Germany
⨯
Silke Gillessen,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation Cantonal Hospital St. Gallen, St. Gallen, Switzerland
⨯
Thomas Joos,

Roles Conceptualization, Supervision, Writing – review & editing

Affiliation NMI Tübingen, Reutlingen, Germany
⨯
Ralph Schiess

Roles Conceptualization, Funding acquisition, Resources, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: schiess@proteomedix.com

Affiliation ProteoMediX Inc., Schlieren, Switzerland

http://orcid.org/0000-0003-4955-1295

⨯

Development and clinical testing of individual immunoassays for the quantification of serum glycoproteins to diagnose prostate cancer

Kathrin Endt,
Jens Goepfert,
Aurelius Omlin,
Alcibiade Athanasiou,
Pierre Tennstedt,
Anna Guenther,
Maurizio Rainisio,
Daniel S. Engeler,
Thomas Steuber,
Silke Gillessen

Published: August 2, 2017
https://doi.org/10.1371/journal.pone.0181557

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Prostate cancer
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Immunoassays
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Biopsy
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Cancer detection and diagnosis
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Prostate gland
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Lung and intrathoracic tumors
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Biomarkers
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Glycoproteins
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