Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1

Arianna Marini; Omar Rossi; Maria Grazia Aruta; Francesca Micoli; Simona Rondini; Serafina Guadagnuolo; Isabel Delany; Ian R. Henderson; Adam F. Cunningham; Allan Saul; Calman A. MacLennan; Oliver Koeberling

doi:10.1371/journal.pone.0181508

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Open Access

Peer-reviewed

Research Article

Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1

Arianna Marini,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Visualization, Writing – original draft, Writing – review & editing

Current address: Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

Affiliations Institute of Immunology and Immunotherapy, College of Medicine and Dental Sciences, University of Birmingham, Birmingham, United Kingdom, GSK Vaccines Institute for Global Health (GVGH), Siena, Italy
⨯
Omar Rossi,

Roles Investigation, Methodology, Writing – review & editing

Current address: Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom

Affiliation GSK Vaccines Institute for Global Health (GVGH), Siena, Italy
⨯
Maria Grazia Aruta,

Roles Investigation, Writing – review & editing

Affiliation GSK Vaccines Institute for Global Health (GVGH), Siena, Italy
⨯
Francesca Micoli,

Roles Investigation, Writing – review & editing

Affiliation GSK Vaccines Institute for Global Health (GVGH), Siena, Italy
⨯
Simona Rondini,

Roles Investigation, Writing – review & editing

Affiliation GSK Vaccines Institute for Global Health (GVGH), Siena, Italy
⨯
Serafina Guadagnuolo,

Roles Methodology, Resources, Writing – review & editing

Current address: Policlinico Universitario Sant'Orsola Malpighi, Bologna, Italy

Affiliation GSK Vaccines, Siena, Italy
⨯
Isabel Delany,

Roles Methodology, Software, Writing – review & editing

Affiliation GSK Vaccines, Siena, Italy
⨯
Ian R. Henderson,

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

Affiliation Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, United Kingdom
⨯
Adam F. Cunningham,

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing

Affiliation Institute of Immunology and Immunotherapy, College of Medicine and Dental Sciences, University of Birmingham, Birmingham, United Kingdom
⨯
Allan Saul,

Roles Conceptualization, Formal analysis, Methodology, Project administration, Software, Visualization, Writing – review & editing

Affiliation GSK Vaccines Institute for Global Health (GVGH), Siena, Italy
⨯
Calman A. MacLennan,

Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – original draft

Current address: Jenner Institute, Nuffield Department of Medicine, University of Oxford, Oxford, United Kingdom

Affiliations Institute of Immunology and Immunotherapy, College of Medicine and Dental Sciences, University of Birmingham, Birmingham, United Kingdom, GSK Vaccines Institute for Global Health (GVGH), Siena, Italy
⨯
Oliver Koeberling

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Supervision, Visualization, Writing – original draft, Writing – review & editing

* E-mail: oliver.x.koeberling@gsk.com

Affiliation GSK Vaccines Institute for Global Health (GVGH), Siena, Italy

http://orcid.org/0000-0001-7904-0184

⨯

Contribution of factor H-Binding protein sequence to the cross-reactivity of meningococcal native outer membrane vesicle vaccines with over-expressed fHbp variant group 1

Arianna Marini,
Omar Rossi,
Maria Grazia Aruta,
Francesca Micoli,
Simona Rondini,
Serafina Guadagnuolo,
Isabel Delany,
Ian R. Henderson,
Adam F. Cunningham,
Allan Saul

Published: July 25, 2017
https://doi.org/10.1371/journal.pone.0181508

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