Pioglitazone ameliorates glomerular NLRP3 inflammasome activation in apolipoprotein E knockout mice with diabetes mellitus

Yao Wang; Bo Yu; Li Wang; Ming Yang; Zhiyin Xia; Wei Wei; Fengyu Zhang; Xiaochen Yuan

doi:10.1371/journal.pone.0181248

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Open Access

Peer-reviewed

Research Article

Pioglitazone ameliorates glomerular NLRP3 inflammasome activation in apolipoprotein E knockout mice with diabetes mellitus

Yao Wang,

Roles Conceptualization, Project administration, Writing – original draft

Affiliation Department of nephrology, the affiliated hospital of Yangzhou University (Yangzhou NO.1 people’s hospital), Yangzhou University, Yangzhou, Jiangsu, China
⨯
Bo Yu,

Roles Methodology, Project administration, Resources

Affiliation Department of emergency, the affiliated hospital of Yangzhou University (Yangzhou NO.1 people’s hospital), Yangzhou University, Yangzhou, Jiangsu, China
⨯
Li Wang,

Roles Project administration, Resources, Software

Affiliation Department of cardiology, the affiliated hospital of Yangzhou University (Yangzhou NO.1 people’s hospital), Yangzhou University, Yangzhou, Jiangsu, China
⨯
Ming Yang,

Roles Conceptualization, Supervision

Affiliation Department of nephrology, the affiliated hospital of Yangzhou University (Yangzhou NO.1 people’s hospital), Yangzhou University, Yangzhou, Jiangsu, China
⨯
Zhiyin Xia,

Roles Supervision, Writing – review & editing

Affiliation Department of nephrology, the affiliated hospital of Yangzhou University (Yangzhou NO.1 people’s hospital), Yangzhou University, Yangzhou, Jiangsu, China
⨯
Wei Wei,

Roles Data curation, Formal analysis

Affiliation Department of nephrology, the affiliated hospital of Yangzhou University (Yangzhou NO.1 people’s hospital), Yangzhou University, Yangzhou, Jiangsu, China
⨯
Fengyu Zhang,

Roles Methodology, Supervision

Affiliation Central lab, the affiliated hospital of Yangzhou University (Yangzhou NO.1 people’s hospital), Yangzhou University, Yangzhou, Jiangsu, China
⨯
Xiaochen Yuan

Roles Funding acquisition, Methodology, Supervision, Writing – review & editing

* E-mail: 1184806497@qq.com

Affiliation Department of cardiology, the affiliated hospital of Yangzhou University (Yangzhou NO.1 people’s hospital), Yangzhou University, Yangzhou, Jiangsu, China

http://orcid.org/0000-0002-2606-4630

⨯

Pioglitazone ameliorates glomerular NLRP3 inflammasome activation in apolipoprotein E knockout mice with diabetes mellitus

Yao Wang,
Bo Yu,
Li Wang,
Ming Yang,
Zhiyin Xia,
Wei Wei,
Fengyu Zhang,
Xiaochen Yuan

Published: July 14, 2017
https://doi.org/10.1371/journal.pone.0181248

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Inflammasomes
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