Pediatric autoimmune hepatitis shows a disproportionate decline of regulatory T cells in the liver and of IL-2 in the blood of patients undergoing therapy

• Jana Diestelhorst ,

  Contributed equally to this work with: Jana Diestelhorst, Norman Junge

  Affiliations Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany, Pediatric Gastroenterology and Hepatology, Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany

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• Norman Junge ,

  Contributed equally to this work with: Jana Diestelhorst, Norman Junge

  Affiliation Pediatric Gastroenterology and Hepatology, Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany

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• Jerome Schlue,

  Affiliation Department of Pathology, Hannover Medical School, Hannover, Germany

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• Christine S. Falk,

  Affiliation Institute of Transplantation Immunology and Integrated Research and Treatment Center Transplantation (IFB-Tx), Hannover Medical School, Hannover, Germany

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• Michael P. Manns,

  Affiliation Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

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• Ulrich Baumann,

  Affiliation Pediatric Gastroenterology and Hepatology, Department of Paediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany

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• Elmar Jaeckel ,

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

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• Richard Taubert

  * E-mail: Taubert.richard@mh-hannover.de

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany

  http://orcid.org/0000-0001-9270-2496

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