Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects

• Marie-Laure Crouch ,

  Contributed equally to this work with: Marie-Laure Crouch, Gary Knowels

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Project administration, Writing – original draft, Writing – review & editing

  Affiliation Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

  http://orcid.org/0000-0001-8099-5826

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• Gary Knowels ,

  Contributed equally to this work with: Marie-Laure Crouch, Gary Knowels

  Roles Investigation

  Affiliation Department of Radiology, School of Medicine, University of Washington, Seattle, Washington, United States of America

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• Rudolph Stuppard,

  Roles Investigation

  Affiliation Department of Radiology, School of Medicine, University of Washington, Seattle, Washington, United States of America

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• Nolan G. Ericson,

  Roles Investigation

  Affiliations Translational Research Program, Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America

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• Jason H. Bielas,

  Roles Methodology, Resources

  Affiliations Translational Research Program, Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Pathology, University of Washington, Seattle, Washington, United States of America

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• David J. Marcinek,

  Roles Conceptualization, Formal analysis, Methodology, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Radiology, School of Medicine, University of Washington, Seattle, Washington, United States of America

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• Karen L. Syrjala

  Roles Conceptualization, Formal analysis, Funding acquisition, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: ksyrjala@fredhutch.org

  Affiliations Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America, Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle, Washington, United States of America

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