The quinic acid derivative KZ-41 prevents glucose-induced caspase-3 activation in retinal endothelial cells through an IGF-1 receptor dependent mechanism

• Hui He,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmaceutical Sciences, UTHSC College of Pharmacy, Memphis, Tennessee, United States of America

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• Rebecca L. Weir,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Software, Writing – original draft, Writing – review & editing

  Affiliation Biochemistry and Cellular and Molecular Biology, The University of Tennessee, Knoxville, Tennessee, United States of America

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• Jordan J. Toutounchian,

  Roles Conceptualization, Methodology, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmaceutical Sciences, UTHSC College of Pharmacy, Memphis, Tennessee, United States of America

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• Jayaprakash Pagadala,

  Roles Data curation, Formal analysis, Methodology, Writing – original draft

  Affiliation Department of Pharmaceutical Sciences, UTHSC College of Pharmacy, Memphis, Tennessee, United States of America

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• Jena J. Steinle,

  Roles Conceptualization, Formal analysis, Project administration, Resources, Writing – original draft

  Affiliation Department of Anatomy, Wayne State University, Detroit, Michigan, United States of America

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• Jerome Baudry,

  Roles Conceptualization, Data curation, Formal analysis, Methodology, Resources, Software, Supervision, Writing – original draft, Writing – review & editing

  Affiliations Biochemistry and Cellular and Molecular Biology, The University of Tennessee, Knoxville, Tennessee, United States of America, UT/ORNL Center for Molecular Biophysics, Oak Ridge National Laboratory, Oak Ridge, Tennessee, United States of America

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• Duane D. Miller,

  Roles Funding acquisition, Resources, Supervision, Writing – original draft, Writing – review & editing

  Affiliation Department of Pharmaceutical Sciences, UTHSC College of Pharmacy, Memphis, Tennessee, United States of America

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• Charles R. Yates

  Roles Conceptualization, Funding acquisition, Investigation, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: cyates4@uthsc.edu

  Affiliations Department of Pharmaceutical Sciences, UTHSC College of Pharmacy, Memphis, Tennessee, United States of America, Department of Ophthalmology, UTHSC College of Medicine, Memphis, Tennessee, United States of America

  http://orcid.org/0000-0002-3730-3844

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