T cell-intrinsic TLR2 stimulation promotes IL-10 expression and suppressive activity by CD45RbHi T cells

Janice C. Jun; Mark B. Jones; Douglas M. Oswald; Edward S. Sim; Amruth R. Jonnalagadda; Lori S. C. Kreisman; Brian A. Cobb

doi:10.1371/journal.pone.0180688

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Open Access

Peer-reviewed

Research Article

T cell-intrinsic TLR2 stimulation promotes IL-10 expression and suppressive activity by CD45Rb^Hi T cells

Janice C. Jun,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliations Case Western Reserve University School of Medicine, Department of Pathology, Cleveland, OH, United States of America, Case Western Reserve University School of Dental Medicine, Cleveland, OH, United States of America
⨯
Mark B. Jones,

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – review & editing

Affiliation Case Western Reserve University School of Medicine, Department of Pathology, Cleveland, OH, United States of America
⨯
Douglas M. Oswald,

Roles Formal analysis, Investigation, Methodology, Resources

Affiliation Case Western Reserve University School of Medicine, Department of Pathology, Cleveland, OH, United States of America
⨯
Edward S. Sim,

Roles Investigation

Affiliation Case Western Reserve University School of Medicine, Department of Pathology, Cleveland, OH, United States of America
⨯
Amruth R. Jonnalagadda,

Roles Formal analysis, Investigation

Affiliation Case Western Reserve University School of Medicine, Department of Pathology, Cleveland, OH, United States of America
⨯
Lori S. C. Kreisman,

Roles Formal analysis, Investigation, Resources

Affiliation Case Western Reserve University School of Medicine, Department of Pathology, Cleveland, OH, United States of America
⨯
Brian A. Cobb

Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: brian.cobb@case.edu

Affiliation Case Western Reserve University School of Medicine, Department of Pathology, Cleveland, OH, United States of America

http://orcid.org/0000-0003-1055-2530

⨯

T cell-intrinsic TLR2 stimulation promotes IL-10 expression and suppressive activity by CD45Rb^Hi T cells

Janice C. Jun,
Mark B. Jones,
Douglas M. Oswald,
Edward S. Sim,
Amruth R. Jonnalagadda,
Lori S. C. Kreisman,
Brian A. Cobb

Published: July 25, 2017
https://doi.org/10.1371/journal.pone.0180688

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