Sativex in resistant multiple sclerosis spasticity: Discontinuation study in a large population of Italian patients (SA.FE. study)

• Silvia Messina ,

  Contributed equally to this work with: Silvia Messina, Francesco Patti

  Roles Conceptualization, Data curation, Formal analysis, Writing – original draft, Writing – review & editing

  Affiliation Department of Medical, Surgical Science and Advanced Technology "GF Ingrassia"–University of Catania, Catania, Italy

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• Claudio Solaro,

  Roles Conceptualization, Data curation, Investigation, Writing – review & editing

  Affiliation Neurology Unit, Department Head And Neck, ASL3 Genova, Italy

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• Isabella Righini,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department NEUROFARBA—University of Florence, Florence, Italy

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• Roberto Bergamaschi,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Neurology—Neurology Institute C Mondino, Pavia, Italy

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• Simona Bonavita,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation I clinic Neurology—II University of Naples, Naples, Italy

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• Roberto Bruno Bossio,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Neurology Operating Unit and Multiple Sclerosis Center—Provincial Health Authority of Cosenza, Cosenza, Italy

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• Vincenzo Brescia Morra,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Centre—University Federico II, Naples, Italy

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• Gianfranco Costantino,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Demyelinating Diseases Centre—Foggia Hospital, Foggia, Italy

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• Paola Cavalla,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation A.O.U: Cittàdella Salute e dellaScienza di Torino, Torino, Italy

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• Diego Centonze,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliations Neuroscience Department—University Tor Vegata, Rome, Italy, Unit of Neurology and of Neurorehabilitation, IRCCS Neuromed, Pozzilli (IS), Italy

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• Giancarlo Comi,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Neurology–San Raffaele Hospital, Milan, Italy

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• Salvatore Cottone,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Neuroimmunology Unit—Villa Sofia-Cervello Hospital, Palermo, Italy

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• Maura Chiara Danni,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Neurology Clinic—Ancona Hospital, Ancona, Italy

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• Ada Francia,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Center, Dept. Neurol. Psich—Sapienza University, Rome, Italy

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• Alberto Gajofatto,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Neuroscience, Biomedicine and Movement Multiple Sclerosis Centre–University of Verona, Verona, Italy

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• Claudio Gasperini,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Neurology Division—San Camillo Hospital, Rome, Italy

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• Mauro Zaffaroni,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Centre—Sant'Antonio Abate Hospital, Gallarate, Italy

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• Loredana Petrucci,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Centre—University Hospital Pisa, Pisa, Italy

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• Elisabetta Signoriello,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Center—Second University of Naples, Naples, Italy

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• Giorgia Teresa Maniscalco,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Centre—Cardarelli Hospital, Naples, Italy

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• Gabriella Spinicci,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Medical Sciences—University of Cagliari, Cagliari, Italy

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• Manuela Matta,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Centre (CRESM)—San Luigi Gonzaga Hospital, Orbassano, Italy

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• Massimiliano Mirabella,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Centre—Cattolica University, Rome, Italy

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• Graziella Pedà,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Centre—Vaio Hospital, Fidenza, Italy

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• Letizia Castelli,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Centre—S. Andrea Hospital, Rome, Italy

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• Marco Rovaris,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Centre—IRCCS Don Gnocchi Foundation, Milan, Italy

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• Edoardo Sessa,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Centre—IRCCS-Bonino Pulejo Centre, Messina, Italy

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• Daniele Spitaleri,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Multiple Sclerosis Centre—San G. Moscati Hospital, Avellino, Italy

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• Damiano Paolicelli,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Basic Medical Sciences, Neuroscience and Sense Organs—University of Bari “Aldo Moro” Bari, Italy

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• Alfredo Granata,

  Roles Formal analysis, Investigation, Writing – review & editing

  Affiliation Department of Medical Sciences, Institute of Neurology—University “Magna Graecia”, Catanzaro, Italy

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• Mario Zappia,

  Roles Investigation, Validation, Writing – review & editing

  Affiliation Department of Medical, Surgical Science and Advanced Technology "GF Ingrassia"–University of Catania, Catania, Italy

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• Francesco Patti ,

  Contributed equally to this work with: Silvia Messina, Francesco Patti

  Roles Conceptualization, Data curation, Investigation, Project administration, Validation, Writing – original draft, Writing – review & editing

  * E-mail: patti@unict.it

  Affiliation Department of Medical, Surgical Science and Advanced Technology "GF Ingrassia"–University of Catania, Catania, Italy

  http://orcid.org/0000-0002-6923-0846

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•  [ ... ],
• on behalf of the SA.FE. study group

  ¶The complete membership of the author group can be found in the Acknowledgments.

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