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Open Access
Peer-reviewed
Research Article
Reverse epithelial-mesenchymal transition contributes to the regain of drug sensitivity in tyrosine kinase inhibitor-resistant non-small cell lung cancer cells
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An-Fu Lee ,
Contributed equally to this work with: An-Fu Lee, Man-Chin Chen
Roles Conceptualization, Data curation, Formal analysis, Investigation, Writing – original draft
Affiliation School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan
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Man-Chin Chen ,
Contributed equally to this work with: An-Fu Lee, Man-Chin Chen
Roles Conceptualization, Data curation, Formal analysis, Investigation
Affiliation Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
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Chao-Ju Chen,
Roles Data curation, Formal analysis, Writing – review & editing
Affiliations Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Department of Laboratory Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
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Chih-Jen Yang ,
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Validation
* E-mail: ypliu@kmu.edu.tw (YPL); shyang@kmu.edu.tw (MSH); chjeya@cc.kmu.edu.tw (CJY)
Affiliations Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, Department of Internal Medicine, School of Medicine, College of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Department of Internal Medicine, Kaohsiung Municipal Ta-Tung Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
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Ming-Shyang Huang ,
Roles Conceptualization, Funding acquisition, Project administration, Supervision, Writing – review & editing
* E-mail: ypliu@kmu.edu.tw (YPL); shyang@kmu.edu.tw (MSH); chjeya@cc.kmu.edu.tw (CJY)
Affiliations Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan, Division of Geriatrics and Gerontology, Department of Internal Medicine, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
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Yu-Peng Liu
Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Project administration, Resources, Supervision, Validation, Writing – original draft, Writing – review & editing
* E-mail: ypliu@kmu.edu.tw (YPL); shyang@kmu.edu.tw (MSH); chjeya@cc.kmu.edu.tw (CJY)
Affiliations Graduate Institute of Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Graduate Institute of Clinical Medicine, Kaohsiung Medical University, Kaohsiung, Taiwan, Center for Infectious Disease and Cancer Research, Kaohsiung Medical University, Kaohsiung, Taiwan, Department of Medical Research, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Kaohsiung, Taiwan
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Reverse epithelial-mesenchymal transition contributes to the regain of drug sensitivity in tyrosine kinase inhibitor-resistant non-small cell lung cancer cells
- An-Fu Lee,
- Man-Chin Chen,
- Chao-Ju Chen,
- Chih-Jen Yang,
- Ming-Shyang Huang,
- Yu-Peng Liu
- Published: July 6, 2017
- https://doi.org/10.1371/journal.pone.0180383