Synthesis and evaluation of L-arabinose-based cationic glycolipids as effective vectors for pDNA and siRNA in vitro

Bo Li; Wanrong Guo; Fan Zhang; Meiyan Liu; Shang Wang; Zhonghua Liu; Shuanglin Xiang; Youlin Zeng

doi:10.1371/journal.pone.0180276

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Open Access

Peer-reviewed

Research Article

Synthesis and evaluation of L-arabinose-based cationic glycolipids as effective vectors for pDNA and siRNA in vitro

Bo Li ,

Contributed equally to this work with: Bo Li, Wanrong Guo

Affiliation National & Local Joint Engineering Laboratory for New Petro-chemical Materials and Fine Utilization of Resources, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan, P. R. China
⨯
Wanrong Guo ,

Contributed equally to this work with: Bo Li, Wanrong Guo

Affiliation National & Local Joint Engineering Laboratory for New Petro-chemical Materials and Fine Utilization of Resources, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan, P. R. China
⨯
Fan Zhang,

Affiliation National & Local Joint Engineering Laboratory for New Petro-chemical Materials and Fine Utilization of Resources, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan, P. R. China
⨯
Meiyan Liu,

Affiliation National & Local Joint Engineering Laboratory for New Petro-chemical Materials and Fine Utilization of Resources, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan, P. R. China
⨯
Shang Wang,

Affiliation Key Laboratory of Protein Chemistry and Developmental Biology of State Education Ministry of China, College of Life Sciences, Hunan Normal University, Changsha, Hunan, P. R. China
⨯
Zhonghua Liu,

Affiliation The National &Local Joint Engineering Laboratory of Animal Peptide Drug Development, College of Life Sciences, Hunan Normal University, Changsha, Hunan, P.R. China
⨯
Shuanglin Xiang,

Affiliation Key Laboratory of Protein Chemistry and Developmental Biology of State Education Ministry of China, College of Life Sciences, Hunan Normal University, Changsha, Hunan, P. R. China
⨯
Youlin Zeng

* E-mail: youlinzengcn@gmail.com

Affiliation National & Local Joint Engineering Laboratory for New Petro-chemical Materials and Fine Utilization of Resources, College of Chemistry and Chemical Engineering, Hunan Normal University, Changsha, Hunan, P. R. China

http://orcid.org/0000-0002-1110-4759

⨯

Synthesis and evaluation of L-arabinose-based cationic glycolipids as effective vectors for pDNA and siRNA in vitro

Bo Li,
Wanrong Guo,
Fan Zhang,
Meiyan Liu,
Shang Wang,
Zhonghua Liu,
Shuanglin Xiang,
Youlin Zeng

Published: July 3, 2017
https://doi.org/10.1371/journal.pone.0180276

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