Cardioprotective effects of PKG activation by soluble GC activator, BAY 60-2770, in ischemia-reperfusion-injured rat hearts

Kyung Hye Lee; So-Ra Lee; Haneul Cho; Jong Shin Woo; Jung Hee Kang; Yun-Mi Jeong; Xian Wu Cheng; Woo-Shik Kim; Weon Kim

doi:10.1371/journal.pone.0180207

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Open Access

Peer-reviewed

Research Article

Cardioprotective effects of PKG activation by soluble GC activator, BAY 60-2770, in ischemia-reperfusion-injured rat hearts

Kyung Hye Lee,

Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Writing – original draft

Affiliation Department of Cardiovascular of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea
⨯
So-Ra Lee,

Roles Data curation, Investigation, Methodology

Affiliation Department of Cardiovascular of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea
⨯
Haneul Cho,

Roles Data curation, Formal analysis, Investigation, Methodology, Visualization

Affiliation Department of Cardiovascular of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea
⨯
Jong Shin Woo,

Roles Data curation, Formal analysis, Methodology

Affiliation Department of Cardiovascular of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea
⨯
Jung Hee Kang,

Roles Formal analysis, Methodology

Affiliation Department of Cardiovascular of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea
⨯
Yun-Mi Jeong,

Roles Formal analysis, Methodology

Affiliation Department of Cardiovascular of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea
⨯
Xian Wu Cheng,

Roles Writing – review & editing

Affiliation Department of Cardiovascular of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea
⨯
Woo-Shik Kim,

Roles Writing – review & editing

Affiliation Department of Cardiovascular of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea
⨯
Weon Kim

Roles Conceptualization, Funding acquisition, Supervision, Writing – review & editing

* E-mail: mylovekw@hanmail.net

Affiliation Department of Cardiovascular of Internal Medicine, Kyung Hee University Hospital, Kyung Hee University, Seoul, Republic of Korea

http://orcid.org/0000-0003-1264-9870

⨯

Cardioprotective effects of PKG activation by soluble GC activator, BAY 60-2770, in ischemia-reperfusion-injured rat hearts

Kyung Hye Lee,
So-Ra Lee,
Haneul Cho,
Jong Shin Woo,
Jung Hee Kang,
Yun-Mi Jeong,
Xian Wu Cheng,
Woo-Shik Kim,
Weon Kim

Published: July 3, 2017
https://doi.org/10.1371/journal.pone.0180207

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Mitochondria
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Heart
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Reperfusion
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Echocardiography
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Cell staining
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Hypoxia
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Ischemia
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Muscle cells
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