RRmix: A method for simultaneous batch effect correction and analysis of metabolomics data in the absence of internal standards

• Stephen Salerno Jr. ,

  Contributed equally to this work with: Stephen Salerno Jr., Mahya Mehrmohamadi

  Roles Conceptualization, Data curation, Formal analysis, Software, Writing – original draft

  Affiliation Department of Biostatistics, University of Michigan, Ann Arbor, Michigan, United States of America

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• Mahya Mehrmohamadi ,

  Contributed equally to this work with: Stephen Salerno Jr., Mahya Mehrmohamadi

  Roles Conceptualization, Data curation, Formal analysis, Project administration, Software, Writing – original draft, Writing – review & editing

  Affiliations Department of Molecular Biology and Genetics, Field of Genomics, Genetics and Development, Cornell University, Ithaca, New York, United States of America, Duke Cancer Institute, Duke Molecular Physiology Institute and Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, United States of America

  http://orcid.org/0000-0002-6681-0810

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• Maria V. Liberti,

  Roles Data curation

  Affiliations Duke Cancer Institute, Duke Molecular Physiology Institute and Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, United States of America, Department of Molecular Biology and Genetics, Field of Biochemistry, Molecular, and Cell Biology, Cornell University, Ithaca, New York, United States of America

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• Muting Wan,

  Roles Data curation, Formal analysis, Software, Writing – original draft

  Affiliation Department of Statistical Science, Cornell University, Ithaca, New York, United States of America

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• Martin T. Wells,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Statistical Science, Cornell University, Ithaca, New York, United States of America

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• James G. Booth,

  Roles Conceptualization, Supervision, Writing – review & editing

  Affiliation Department of Statistical Science, Cornell University, Ithaca, New York, United States of America

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• Jason W. Locasale

  Roles Conceptualization, Data curation, Project administration, Supervision, Writing – review & editing

  * E-mail: jason.locasale@duke.edu

  Affiliations Department of Molecular Biology and Genetics, Field of Genomics, Genetics and Development, Cornell University, Ithaca, New York, United States of America, Duke Cancer Institute, Duke Molecular Physiology Institute and Department of Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, North Carolina, United States of America, Department of Molecular Biology and Genetics, Field of Biochemistry, Molecular, and Cell Biology, Cornell University, Ithaca, New York, United States of America

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