Survival, bacterial clearance and thrombocytopenia are improved in polymicrobial sepsis by targeting nuclear transport shuttles

• Ruth Ann Veach,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Project administration, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

  Affiliations Immunotherapy Program at Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

  ⨯
• Yan Liu,

  Roles Investigation, Resources, Validation

  Affiliations Immunotherapy Program at Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

  ⨯
• Jozef Zienkiewicz,

  Roles Conceptualization, Formal analysis, Investigation, Methodology, Visualization, Writing – review & editing

  Affiliations Immunotherapy Program at Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Veterans Affairs, Tennessee Valley Health Care System, Nashville, Tennessee, United States of America

  ⨯
• Lukasz S. Wylezinski,

  Roles Investigation, Writing – review & editing

  Affiliations Immunotherapy Program at Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

  ⨯
• Kelli L. Boyd,

  Roles Investigation, Methodology, Resources

  Affiliation Department of Pathology, Microbiology and Immunology, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

  ⨯
• James L. Wynn,

  Roles Conceptualization, Methodology, Writing – review & editing

  Affiliations Department of Pediatrics, University of Florida, Gainesville, Florida, United States of America, Department of Pathology, Immunology, and Laboratory Medicine, University of Florida, Gainesville, Florida, United States of America

  ⨯
• Jacek Hawiger

  Roles Conceptualization, Funding acquisition, Methodology, Project administration, Supervision, Writing – original draft, Writing – review & editing

  * E-mail: jack.hawiger@vanderbilt.edu

  Affiliations Immunotherapy Program at Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Medicine, Division of Allergy, Pulmonary and Critical Care Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America, Department of Veterans Affairs, Tennessee Valley Health Care System, Nashville, Tennessee, United States of America, Department of Molecular Physiology and Biophysics, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America

  http://orcid.org/0000-0003-2721-6859

  ⨯