Computational explanation for bioactivation mechanism of targeted anticancer agents mediated by cytochrome P450s: A case of Erlotinib

• Chun-Zhi Ai,

  Affiliations Institute for Advanced Study, Shenzhen University, Shenzhen, Guangdong, China, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong, China

  http://orcid.org/0000-0002-4194-6690

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• Yong Liu,

  Affiliation School of Life Science and Medicine, Dalian University of Technology, Panjin, Liaoning, China

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• Wei Li,

  Affiliation College of Medicine, Yangzhou University, Yangzhou, Jiangsu, China

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• De-Meng Chen,

  Affiliations Institute for Advanced Study, Shenzhen University, Shenzhen, Guangdong, China, School of Dentistry, University of California, Los Angeles, California, United States of America

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• Xin-Xing Zhu,

  Affiliations Institute for Advanced Study, Shenzhen University, Shenzhen, Guangdong, China, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong, China

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• Ya-Wei Yan,

  Affiliations Institute for Advanced Study, Shenzhen University, Shenzhen, Guangdong, China, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong, China

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• Du-Chu Chen,

  Affiliations Institute for Advanced Study, Shenzhen University, Shenzhen, Guangdong, China, Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen, Guangdong, China

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• Yi-Zhou Jiang

  * E-mail: jiangyz@szu.edu.cn

  Affiliation Institute for Advanced Study, Shenzhen University, Shenzhen, Guangdong, China

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