Potentiated virucidal activity of pomegranate rind extract (PRE) and punicalagin against Herpes simplex virus (HSV) when co-administered with zinc (II) ions, and antiviral activity of PRE against HSV and aciclovir-resistant HSV

• David M. J. Houston ,

  Roles Conceptualization, Data curation, Formal analysis, Investigation, Methodology, Validation, Writing – original draft

  ¶‡ These authors are joint senior authors on this work.

  Affiliations School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff Wales, United Kingdom, Department of Microbiology and Infectious Diseases, School of Medicine, Cardiff University, Cardiff Wales, United Kingdom

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• Joachim J. Bugert,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation

  Current address: Institut für Mikrobiologie der Bundeswehr, Neuherbergstraße 11, München, Germany

  Affiliation Department of Microbiology and Infectious Diseases, School of Medicine, Cardiff University, Cardiff Wales, United Kingdom

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• Stephen P. Denyer,

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Methodology, Project administration, Resources, Supervision, Validation, Writing – original draft

  Current address: University of Brighton, Mithras House, Lewes Road, Brighton, United Kingdom

  Affiliation School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff Wales, United Kingdom

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• Charles M. Heard

  Roles Conceptualization, Data curation, Formal analysis, Funding acquisition, Investigation, Methodology, Project administration, Resources, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

  * E-mail: heard@cardiff.ac.uk

  ¶‡ These authors are joint senior authors on this work.

  Affiliation School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff Wales, United Kingdom

  http://orcid.org/0000-0001-9703-9777

  ⨯