Ligand-mediated and tertiary interactions cooperatively stabilize the P1 region in the guanine-sensing riboswitch

Open Access

Peer-reviewed

Research Article

Christian A. Hanke,

Affiliation Mathematisch-Naturwissenschaftliche Fakultät, Institut für Pharmazeutische und Medizinische Chemie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany
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Holger Gohlke

* E-mail: gohlke@uni-duesseldorf.de

Affiliation Mathematisch-Naturwissenschaftliche Fakultät, Institut für Pharmazeutische und Medizinische Chemie, Heinrich-Heine-Universität Düsseldorf, Düsseldorf, Germany

http://orcid.org/0000-0001-8613-1447

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Nucleotides
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Biochemical simulations
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RNA structure
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Crystal structure
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Riboswitches
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Hydrogen bonding
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Binding analysis
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Molecular dynamics
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