Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB

Si-yong Gao; Guang-sen Zheng; Lin Wang; Yu-jie Liang; Si-en Zhang; Xiao-mei Lao; Kan Li; Gui-qing Liao

doi:10.1371/journal.pone.0179248

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Peer-reviewed

Research Article

Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB

Si-yong Gao ,

Contributed equally to this work with: Si-yong Gao, Guang-sen Zheng

Affiliation Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory, Sun Yat-Sen University, Guangzhou, China
⨯
Guang-sen Zheng ,

Contributed equally to this work with: Si-yong Gao, Guang-sen Zheng

Affiliation Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory, Sun Yat-Sen University, Guangzhou, China
⨯
Lin Wang,

Affiliation Department of Oral Implant, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory, Sun Yat-Sen University, Guangzhou, China
⨯
Yu-jie Liang,

Affiliation Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory, Sun Yat-Sen University, Guangzhou, China
⨯
Si-en Zhang,

Affiliation Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory, Sun Yat-Sen University, Guangzhou, China
⨯
Xiao-mei Lao,

Affiliation Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory, Sun Yat-Sen University, Guangzhou, China
⨯
Kan Li,

Affiliation Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory, Sun Yat-Sen University, Guangzhou, China
⨯
Gui-qing Liao

* E-mail: drliaoguiqing@hotmail.com

Current address: Department of Oral and Maxillofacial Surgery, Guanghua School of stomatology, Guangzhou, Guangdong, China

Affiliation Department of Oral and Maxillofacial Surgery, Guanghua School of Stomatology, Guangdong Provincial Key Laboratory, Sun Yat-Sen University, Guangzhou, China
⨯

Zoledronate suppressed angiogenesis and osteogenesis by inhibiting osteoclasts formation and secretion of PDGF-BB

Si-yong Gao,
Guang-sen Zheng,
Lin Wang,
Yu-jie Liang,
Si-en Zhang,
Xiao-mei Lao,
Kan Li,
Gui-qing Liao

Published: June 8, 2017
https://doi.org/10.1371/journal.pone.0179248

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