Comparison between intra-articular ozone and placebo in the treatment of knee osteoarthritis: A randomized, double-blinded, placebo-controlled study

Carlos César Lopes de Jesus; Fânia Cristina dos Santos; Luciana Maria Oliveira Bueno de Jesus; Iara Monteiro; Maria Sonia Sousa Castro Sant’Ana; Virginia Fernandes Moça Trevisani

doi:10.1371/journal.pone.0179185

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Open Access

Peer-reviewed

Research Article

Comparison between intra-articular ozone and placebo in the treatment of knee osteoarthritis: A randomized, double-blinded, placebo-controlled study

Carlos César Lopes de Jesus ,

Roles Conceptualization, Data curation, Investigation, Methodology, Resources, Validation, Visualization, Writing – original draft, Writing – review & editing

* E-mail: caceloje@gmail.com

Affiliation Department of Evidence-Based Medicine, Paulista School of Medicine, Sao Paulo Federal University, Sao Paulo, Sao Paulo, Brazil

http://orcid.org/0000-0002-0951-5508

⨯
Fânia Cristina dos Santos,

Roles Data curation, Investigation, Methodology, Resources, Software, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Geriatrics and Gerontology, Paulista School of Medicine, Sao Paulo Federal University, Sao Paulo, Sao Paulo, Brazil
⨯
Luciana Maria Oliveira Bueno de Jesus,

Roles Data curation, Investigation, Resources, Validation, Writing – original draft, Writing – review & editing

Affiliation ”Dante Pazzanese” Institute of Cardiology, Sao Paulo, Sao Paulo, Brazil
⨯
Iara Monteiro,

Roles Data curation, Investigation, Resources, Validation, Writing – original draft, Writing – review & editing

Affiliation Department of Geriatrics and Gerontology, Paulista School of Medicine, Sao Paulo Federal University, Sao Paulo, Sao Paulo, Brazil
⨯
Maria Sonia Sousa Castro Sant’Ana,

Roles Data curation, Investigation, Resources, Validation, Writing – original draft, Writing – review & editing

Affiliation Department of Geriatrics and Gerontology, Paulista School of Medicine, Sao Paulo Federal University, Sao Paulo, Sao Paulo, Brazil
⨯
Virginia Fernandes Moça Trevisani

Roles Data curation, Investigation, Methodology, Supervision, Validation, Visualization, Writing – original draft, Writing – review & editing

Affiliation Department of Evidence-Based Medicine, Paulista School of Medicine, Sao Paulo Federal University, Sao Paulo, Sao Paulo, Brazil
⨯

Comparison between intra-articular ozone and placebo in the treatment of knee osteoarthritis: A randomized, double-blinded, placebo-controlled study

Carlos César Lopes de Jesus,
Fânia Cristina dos Santos,
Luciana Maria Oliveira Bueno de Jesus,
Iara Monteiro,
Maria Sonia Sousa Castro Sant’Ana,
Virginia Fernandes Moça Trevisani

Published: July 24, 2017
https://doi.org/10.1371/journal.pone.0179185

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Ozone
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Pain
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Osteoarthritis
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Knees
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Geriatrics
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Quality of life
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Knee joints
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Skeletal joints
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