A prospective pilot study of genome-wide exome and transcriptome profiling in patients with small cell lung cancer progressing after first-line therapy

Glen J. Weiss; Sara A. Byron; Jessica Aldrich; Ashish Sangal; Heather Barilla; Jeffrey A. Kiefer; John D. Carpten; David W. Craig; Timothy G. Whitsett

doi:10.1371/journal.pone.0179170

Loading metrics

Open Access

Peer-reviewed

Research Article

A prospective pilot study of genome-wide exome and transcriptome profiling in patients with small cell lung cancer progressing after first-line therapy

Glen J. Weiss ,

* E-mail: glen.weiss@ctca-hope.com

Affiliations Western Regional Medical Center, Cancer Treatment Centers of America, Goodyear, Arizona, United States of America, Translational Genomics Research Institute, Phoenix, Arizona, United States of America

http://orcid.org/0000-0002-6067-597X

⨯
Sara A. Byron,

Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America
⨯
Jessica Aldrich,

Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America
⨯
Ashish Sangal,

Affiliation Western Regional Medical Center, Cancer Treatment Centers of America, Goodyear, Arizona, United States of America
⨯
Heather Barilla,

Affiliation Western Regional Medical Center, Cancer Treatment Centers of America, Goodyear, Arizona, United States of America
⨯
Jeffrey A. Kiefer,

Current address: Systems Oncology, Scottsdale, Arizona, United States of America

Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America
⨯
John D. Carpten,

Current address: Department of Translational Genomics, Keck School of Medicine, University of Southern California, Los Angeles, California, United Stated of America

Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America
⨯
David W. Craig ,

Current address: Department of Translational Genomics, Keck School of Medicine, University of Southern California, Los Angeles, California, United Stated of America

¶‡ DWC and TGW are Joint Senior Authors.

Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America
⨯
Timothy G. Whitsett

Current address: Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Dignity Health, Phoenix, Arizona, United States of America

¶‡ DWC and TGW are Joint Senior Authors.

Affiliation Translational Genomics Research Institute, Phoenix, Arizona, United States of America
⨯

A prospective pilot study of genome-wide exome and transcriptome profiling in patients with small cell lung cancer progressing after first-line therapy

Glen J. Weiss,
Sara A. Byron,
Jessica Aldrich,
Ashish Sangal,
Heather Barilla,
Jeffrey A. Kiefer,
John D. Carpten,
David W. Craig,
Timothy G. Whitsett

Published: June 6, 2017
https://doi.org/10.1371/journal.pone.0179170

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Cancer treatment
Is the Subject Area "Cancer treatment" applicable to this article?

Thanks for your feedback.
Small cell lung cancer
Is the Subject Area "Small cell lung cancer" applicable to this article?

Thanks for your feedback.
Cancers and neoplasms
Is the Subject Area "Cancers and neoplasms" applicable to this article?

Thanks for your feedback.
Next-generation sequencing
Is the Subject Area "Next-generation sequencing" applicable to this article?

Thanks for your feedback.
Lung and intrathoracic tumors
Is the Subject Area "Lung and intrathoracic tumors" applicable to this article?

Thanks for your feedback.
Cancer genomics
Is the Subject Area "Cancer genomics" applicable to this article?

Thanks for your feedback.
Malignant tumors
Is the Subject Area "Malignant tumors" applicable to this article?

Thanks for your feedback.
RNA sequencing
Is the Subject Area "RNA sequencing" applicable to this article?

Thanks for your feedback.