Long-term efficacy and safety of nalfurafine hydrochloride on pruritus in chronic liver disease patients: Patient-reported outcome based analyses

Kenya Kamimura; Takeshi Yokoo; Hiroteru Kamimura; Akira Sakamaki; Satoshi Abe; Atsunori Tsuchiya; Masaaki Takamura; Hirokazu Kawai; Satoshi Yamagiwa; Shuji Terai

doi:10.1371/journal.pone.0178991

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Open Access

Peer-reviewed

Research Article

Long-term efficacy and safety of nalfurafine hydrochloride on pruritus in chronic liver disease patients: Patient-reported outcome based analyses

Kenya Kamimura ,

* E-mail: kenya-k@med.niigata-u.ac.jp

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachido-ri, Chuo-ku, Niigata, Niigata, Japan

http://orcid.org/0000-0001-7182-4400

⨯
Takeshi Yokoo,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachido-ri, Chuo-ku, Niigata, Niigata, Japan
⨯
Hiroteru Kamimura,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachido-ri, Chuo-ku, Niigata, Niigata, Japan
⨯
Akira Sakamaki,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachido-ri, Chuo-ku, Niigata, Niigata, Japan
⨯
Satoshi Abe,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachido-ri, Chuo-ku, Niigata, Niigata, Japan
⨯
Atsunori Tsuchiya,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachido-ri, Chuo-ku, Niigata, Niigata, Japan
⨯
Masaaki Takamura,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachido-ri, Chuo-ku, Niigata, Niigata, Japan
⨯
Hirokazu Kawai,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachido-ri, Chuo-ku, Niigata, Niigata, Japan
⨯
Satoshi Yamagiwa,

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachido-ri, Chuo-ku, Niigata, Niigata, Japan
⨯
Shuji Terai

Affiliation Division of Gastroenterology and Hepatology, Graduate School of Medical and Dental Sciences, Niigata University, Asahimachido-ri, Chuo-ku, Niigata, Niigata, Japan
⨯

Long-term efficacy and safety of nalfurafine hydrochloride on pruritus in chronic liver disease patients: Patient-reported outcome based analyses

Kenya Kamimura,
Takeshi Yokoo,
Hiroteru Kamimura,
Akira Sakamaki,
Satoshi Abe,
Atsunori Tsuchiya,
Masaaki Takamura,
Hirokazu Kawai,
Satoshi Yamagiwa,
Shuji Terai

Published: June 12, 2017
https://doi.org/10.1371/journal.pone.0178991

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Pruritus
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Chronic liver disease
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Drug therapy
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Liver diseases
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Aminotransferases
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Anemia
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Bilirubin
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Medical dialysis
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