Cucurbitacin E reduces obesity and related metabolic dysfunction in mice by targeting JAK-STAT5 signaling pathway

Munazza Murtaza; Gulnaz Khan; Meha Fatima Aftab; Shabbir Khan Afridi; Safina Ghaffar; Ayaz Ahmed; Rahman M. Hafizur; Rizwana Sanaullah Waraich

doi:10.1371/journal.pone.0178910

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Open Access

Peer-reviewed

Research Article

Cucurbitacin E reduces obesity and related metabolic dysfunction in mice by targeting JAK-STAT5 signaling pathway

Munazza Murtaza,

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
⨯
Gulnaz Khan,

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
⨯
Meha Fatima Aftab,

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
⨯
Shabbir Khan Afridi,

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
⨯
Safina Ghaffar,

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
⨯
Ayaz Ahmed,

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
⨯
Rahman M. Hafizur,

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan
⨯
Rizwana Sanaullah Waraich

* E-mail: rizwanas.waraich@gmail.com

Affiliation Dr. Panjwani Center for Molecular Medicine and Drug Research, International Center for Chemical and Biological Sciences, University of Karachi, Karachi, Pakistan

http://orcid.org/0000-0002-5560-5053

⨯

Cucurbitacin E reduces obesity and related metabolic dysfunction in mice by targeting JAK-STAT5 signaling pathway

Munazza Murtaza,
Gulnaz Khan,
Meha Fatima Aftab,
Shabbir Khan Afridi,
Safina Ghaffar,
Ayaz Ahmed,
Rahman M. Hafizur,
Rizwana Sanaullah Waraich

Published: June 9, 2017
https://doi.org/10.1371/journal.pone.0178910

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