IGF1 and IGF2 specificities to the two insulin receptor isoforms are determined by insulin receptor amino acid 718

Open Access

Peer-reviewed

Research Article

Mie Andersen,

Affiliation Novo Nordisk, Novo Nordisk Park, Maaloev, Denmark
⨯
Dorte Nørgaard-Pedersen,

Affiliation Novo Nordisk, Novo Nordisk Park, Maaloev, Denmark
⨯
Jakob Brandt,

Affiliation Novo Nordisk, Novo Nordisk Park, Maaloev, Denmark
⨯
Ingrid Pettersson,

Affiliation Novo Nordisk, Novo Nordisk Park, Maaloev, Denmark
⨯
Rita Slaaby

* E-mail: risl@novonordisk.com

Affiliation Novo Nordisk, Novo Nordisk Park, Maaloev, Denmark

http://orcid.org/0000-0002-2038-8466

⨯

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Insulin
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Binding analysis
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Phosphorylation
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Receptor binding assays
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Amino acid analysis
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Crystal structure
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Mutational analysis
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Protein structure comparison
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