Effects of two different decellularization routes on the mechanical properties of decellularized lungs

Jessica Julioti Urbano; Renata Kelly da Palma; Flávia Mafra de Lima; Paula Fratini; Leticia Lopes Guimaraes; Juan J. Uriarte; Letícia Heineck Alvarenga; Maria Angelica Miglino; Rodolfo de Paula Vieira; Renato Araujo Prates; Daniel Navajas; Ramon Farrè; Luis Vicente Franco Oliveira

doi:10.1371/journal.pone.0178696

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Open Access

Peer-reviewed

Research Article

Effects of two different decellularization routes on the mechanical properties of decellularized lungs

Jessica Julioti Urbano,

Affiliation Experimental Cardiorespiratory Physiology Laboratory, Master’s Degree and PhD Program in Rehabilitation Sciences, Nove de Julho University, Sao Paulo, Brazil
⨯
Renata Kelly da Palma,

Affiliation Experimental Cardiorespiratory Physiology Laboratory, Master’s Degree and PhD Program in Rehabilitation Sciences, Nove de Julho University, Sao Paulo, Brazil
⨯
Flávia Mafra de Lima,

Affiliation Laboratory of Clinical and Experimental Immunology, Department of Medicine, Division of Nephrology, Federal University of São Paulo (UNIFESP), Sao Paulo, Brazil
⨯
Paula Fratini,

Affiliation Department of Surgery, Faculty of the Veterinary Medicine and Zootecny, São Paulo University, São Paulo, Brazil
⨯
Leticia Lopes Guimaraes,

Affiliation Experimental Cardiorespiratory Physiology Laboratory, Master’s Degree and PhD Program in Rehabilitation Sciences, Nove de Julho University, Sao Paulo, Brazil
⨯
Juan J. Uriarte,

Affiliation Unitat Biofísica i Bioenginyeria, Facultat de Medicina, Universitat de Barcelona-IDIBAPS-IBEC-CIBER de Enfermedades Respiratorias, Barcelona, Spain
⨯
Letícia Heineck Alvarenga,

Affiliation Master's and Doctoral Program in Biophotonics Applied to Health Sciences, Nove de Julho University, Sao Paulo, Brazil
⨯
Maria Angelica Miglino,

Affiliation Department of Surgery, Faculty of the Veterinary Medicine and Zootecny, São Paulo University, São Paulo, Brazil
⨯
Rodolfo de Paula Vieira,

Affiliation Experimental Cardiorespiratory Physiology Laboratory, Master’s Degree and PhD Program in Rehabilitation Sciences, Nove de Julho University, Sao Paulo, Brazil
⨯
Renato Araujo Prates,

Affiliation Master's and Doctoral Program in Biophotonics Applied to Health Sciences, Nove de Julho University, Sao Paulo, Brazil
⨯
Daniel Navajas,

Affiliation Unitat Biofísica i Bioenginyeria, Facultat de Medicina, Universitat de Barcelona-IDIBAPS-IBEC-CIBER de Enfermedades Respiratorias, Barcelona, Spain
⨯
Ramon Farrè,

Affiliation Unitat Biofísica i Bioenginyeria, Facultat de Medicina, Universitat de Barcelona-IDIBAPS-IBEC-CIBER de Enfermedades Respiratorias, Barcelona, Spain
⨯
Luis Vicente Franco Oliveira

* E-mail: oliveira.lvf@uninove.br

Affiliation Experimental Cardiorespiratory Physiology Laboratory, Master’s Degree and PhD Program in Rehabilitation Sciences, Nove de Julho University, Sao Paulo, Brazil

http://orcid.org/0000-0002-3852-9415

⨯

Effects of two different decellularization routes on the mechanical properties of decellularized lungs

Jessica Julioti Urbano,
Renata Kelly da Palma,
Flávia Mafra de Lima,
Paula Fratini,
Leticia Lopes Guimaraes,
Juan J. Uriarte,
Letícia Heineck Alvarenga,
Maria Angelica Miglino,
Rodolfo de Paula Vieira,
Renato Araujo Prates

Published: June 1, 2017
https://doi.org/10.1371/journal.pone.0178696

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Pulmonary arteries
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Trachea
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Lungs
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Mechanical properties
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Scanning electron microscopy
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Pulmonary imaging
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Lung transplantation
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Extracellular matrix
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