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Open Access
Peer-reviewed
Research Article
Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma
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Antonio Aguilar-Pimentel ,
Contributed equally to this work with: Antonio Aguilar-Pimentel, Anke Graessel
¶‡ SB, JG, and CBS-W also contributed equally to this work. AA-P and AG are co-first authors on this work. SB, JG, and CBS-W are joint senior authors on this work.
Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Center Munich, Neuherberg, Germany
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Anke Graessel ,
Contributed equally to this work with: Antonio Aguilar-Pimentel, Anke Graessel
¶‡ SB, JG, and CBS-W also contributed equally to this work. AA-P and AG are co-first authors on this work. SB, JG, and CBS-W are joint senior authors on this work.
Affiliation Center of Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Center Munich, Member of the German Center for Lung research (DZL), Munich, Germany
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Francesca Alessandrini,
Affiliation Center of Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Center Munich, Member of the German Center for Lung research (DZL), Munich, Germany
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Helmut Fuchs,
Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Center Munich, Neuherberg, Germany
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Valerie Gailus-Durner,
Affiliation German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Center Munich, Neuherberg, Germany
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Martin Hrabě de Angelis,
Affiliations German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Center Munich, Neuherberg, Germany, Experimental Genetics, School of Life Science Weihenstephan, Technical University of Munich, Freising, Germany
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Dennis Russkamp,
Affiliation Center of Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Center Munich, Member of the German Center for Lung research (DZL), Munich, Germany
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Adam Chaker,
Affiliations Center of Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Center Munich, Member of the German Center for Lung research (DZL), Munich, Germany, Department of Otolaryngology, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany
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Markus Ollert,
Affiliations Department of Infection and Immunity, Luxembourg Institute of Health (LIH), Esch-sur-Alzette, Luxembourg, Department of Dermatology and Allergy Center, Odense Research Center for Anaphylaxis, University of Southern Denmark, Odense, Denmark
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Simon Blank ,
¶‡ SB, JG, and CBS-W also contributed equally to this work. AA-P and AG are co-first authors on this work. SB, JG, and CBS-W are joint senior authors on this work.
Affiliation Center of Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Center Munich, Member of the German Center for Lung research (DZL), Munich, Germany
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Jan Gutermuth ,
¶‡ SB, JG, and CBS-W also contributed equally to this work. AA-P and AG are co-first authors on this work. SB, JG, and CBS-W are joint senior authors on this work.
Affiliation Department of Dermatology, Universitair Ziekenhuis Brussel, Vrije Universiteit Brussel, Brussels, Belgium
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Carsten B. Schmidt-Weber
* E-mail: csweber@tum.de
¶‡ SB, JG, and CBS-W also contributed equally to this work. AA-P and AG are co-first authors on this work. SB, JG, and CBS-W are joint senior authors on this work.
Affiliation Center of Allergy and Environment (ZAUM), Technical University of Munich and Helmholtz Center Munich, Member of the German Center for Lung research (DZL), Munich, Germany
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Improved efficacy of allergen-specific immunotherapy by JAK inhibition in a murine model of allergic asthma
- Antonio Aguilar-Pimentel,
- Anke Graessel,
- Francesca Alessandrini,
- Helmut Fuchs,
- Valerie Gailus-Durner,
- Martin Hrabě de Angelis,
- Dennis Russkamp,
- Adam Chaker,
- Markus Ollert,
- Simon Blank
- Published: June 1, 2017
- https://doi.org/10.1371/journal.pone.0178563