Spontaneous low frequency BOLD signal variations from resting-state fMRI are decreased in Alzheimer disease

• Samaneh Kazemifar ,

  Contributed equally to this work with: Samaneh Kazemifar, Ravi S. Menon, Robert Bartha

  Affiliations Centre for Functional and Metabolic Mapping, Robarts Research Institute, University of Western Ontario, London, Ontario, Canada, Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada

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• Kathryn Y. Manning ,

  ¶‡ These authors also contributed equally to this work.

  Affiliations Centre for Functional and Metabolic Mapping, Robarts Research Institute, University of Western Ontario, London, Ontario, Canada, Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada

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• Nagalingam Rajakumar ,

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Anatomy and Cell Biology, University of Western Ontario, London, Ontario, Canada

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• Francisco A. Gómez ,

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Mathematics, Universidad Nacional de Colombia, Sede Bogotá, Colombia

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• Andrea Soddu ,

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Physics and Astronomy, University of Western Ontario, London, Ontario, Canada

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• Michael J. Borrie ,

  ¶‡ These authors also contributed equally to this work.

  Affiliations Department of Medicine, University of Western Ontario, London, Ontario, Canada, Division of Aging, Rehabilitation and Geriatric Care, Lawson Health Research Institute, London, Ontario, Canada

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• Ravi S. Menon ,

  Contributed equally to this work with: Samaneh Kazemifar, Ravi S. Menon, Robert Bartha

  Affiliations Centre for Functional and Metabolic Mapping, Robarts Research Institute, University of Western Ontario, London, Ontario, Canada, Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada

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• Robert Bartha ,

  Contributed equally to this work with: Samaneh Kazemifar, Ravi S. Menon, Robert Bartha

  * E-mail: rbartha@robarts.ca

  Affiliations Centre for Functional and Metabolic Mapping, Robarts Research Institute, University of Western Ontario, London, Ontario, Canada, Department of Medical Biophysics, University of Western Ontario, London, Ontario, Canada

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• for the Alzheimer’s Disease Neuroimaging Initiative

  ¶Membership of the Alzheimer’s Disease Neuroimaging Initiative is provided in the Acknowledgments.

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