An ancestral haplotype of the human PERIOD2 gene associates with reduced sensitivity to light-induced melatonin suppression

• Tokiho Akiyama,

  Affiliations Department of Anatomy, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan, Department of Biosciences, School of Science, Kitasato University, Sagamihara, Kanagawa, Japan, Department of Evolutionary Studies of Biosystems, SOKENDAI (The Graduate University for Advanced Studies), Hayama, Kanagawa, Japan

  http://orcid.org/0000-0002-9050-1014

  ⨯
• Takafumi Katsumura,

  Affiliation Department of Anatomy, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan

  ⨯
• Shigeki Nakagome,

  Affiliations Department of Mathematical Analysis and Statistical Inference, The Institute of Statistical Mathematics, Tachikawa, Tokyo, Japan, Department of Human Genetics, University of Chicago, Chicago, Illinois, United States of America

  ⨯
• Sang-il Lee,

  Affiliation Department of Human Science, Faculty of Design, Kyushu University, Minami-ku Fukuoka, Japan

  ⨯
• Keiichiro Joh,

  Affiliation Division of Molecular Genetics and Epigenetics, Department of Biomolecular Science, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan

  ⨯
• Hidenobu Soejima,

  Affiliation Division of Molecular Genetics and Epigenetics, Department of Biomolecular Science, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan

  ⨯
• Kazuma Fujimoto,

  Affiliation Department of Internal Medicine, Faculty of Medicine, Saga University, Nabeshima, Saga, Japan

  ⨯
• Ryosuke Kimura,

  Affiliation Department of Human Biology and Anatomy, Faculty of Medicine, University of the Ryukyus, Nishihara-cho, Okinawa, Japan

  ⨯
• Hajime Ishida,

  Affiliation Department of Human Biology and Anatomy, Faculty of Medicine, University of the Ryukyus, Nishihara-cho, Okinawa, Japan

  ⨯
• Tsunehiko Hanihara,

  Affiliations Department of Anatomy, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan, Department of Biological Structure, Kitasato University Graduate School of Medical Sciences, Sagamihara, Kanagawa, Japan

  ⨯
• Akira Yasukouchi,

  Affiliation Department of Human Science, Faculty of Design, Kyushu University, Minami-ku Fukuoka, Japan

  ⨯
• Yoko Satta,

  Affiliation Department of Evolutionary Studies of Biosystems, SOKENDAI (The Graduate University for Advanced Studies), Hayama, Kanagawa, Japan

  ⨯
• Shigekazu Higuchi ,

  * E-mail: higu-s@design.kyushu-u.ac.jp (SH); hiroki_oota@med.kitasato-u.ac.jp (HO)

  Affiliation Department of Human Science, Faculty of Design, Kyushu University, Minami-ku Fukuoka, Japan

  ⨯
• Hiroki Oota

  * E-mail: higu-s@design.kyushu-u.ac.jp (SH); hiroki_oota@med.kitasato-u.ac.jp (HO)

  Affiliations Department of Anatomy, Kitasato University School of Medicine, Sagamihara, Kanagawa, Japan, Department of Biological Structure, Kitasato University Graduate School of Medical Sciences, Sagamihara, Kanagawa, Japan

  ⨯