Integrating Tenascin-C protein expression and 1q25 copy number status in pediatric intracranial ependymoma prognostication: A new model for risk stratification

• Felipe Andreiuolo ,

  Contributed equally to this work with: Felipe Andreiuolo, Gwénaël Le Teuff

  Affiliations Université Paris-Sud, Gustave Roussy, CNRS UMR 8203 "Vectorologie et Thérapeutiques Anticancéreuses", Villejuif, France, Département de Neuropathologie, Hôpital Sainte-Anne, Paris, France, Departamento de Patologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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• Gwénaël Le Teuff ,

  Contributed equally to this work with: Felipe Andreiuolo, Gwénaël Le Teuff

  Affiliations Departement de Biostatistique et Epidemiologie, Gustave Roussy, Cancer Campus, Grand Paris, Villejuif, France, CESP Centre for Research in Epidemiology and Population Health, INSERM U1018, Paris-Sud Univ., Villejuif, France

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• Mohamed Amine Bayar,

  Affiliations Departement de Biostatistique et Epidemiologie, Gustave Roussy, Cancer Campus, Grand Paris, Villejuif, France, CESP Centre for Research in Epidemiology and Population Health, INSERM U1018, Paris-Sud Univ., Villejuif, France

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• John-Paul Kilday,

  Affiliations Children’s Brain Tumour Research Network (CBTRN), Royal Manchester Children’s Hospital, Manchester, United Kingdom, The Centre for Paediatric, Teenage and Young Adult Cancer, Institute of Cancer Sciences, The University of Manchester, Manchester, United Kingdom

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• Torsten Pietsch,

  Affiliation Institute of Neuropathology, University of Bonn Medical Center, Bonn, Germany

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• André O. von Bueren,

  Affiliations Department of Paediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University Medical Center Goettingen, Goettingen, Germany

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• Hendrik Witt,

  Affiliation Division of Paediatric Neurooncology, German Cancer Research Center (DKFZ) and Department of Paediatric Oncology, Heidelberg University Hospital, Heidelberg, Germany

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• Andrey Korshunov,

  Affiliation Clinical Cooperation Unit Neuropathology, German Cancer Research Center (DKFZ), Heidelberg, Germany

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• Piergiorgio Modena,

  Affiliation Genetics Unit, Pathology Department, Ospedale S. Anna, Como, Italy

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• Stefan M. Pfister,

  Affiliation Division of Paediatric Neurooncology, German Cancer Research Center (DKFZ) and Department of Paediatric Oncology, Heidelberg University Hospital, Heidelberg, Germany

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• Mélanie Pagès,

  Affiliations Département de Neuropathologie, Hôpital Sainte-Anne, Paris, France, Université Sorbonne Paris Cité, Paris, France

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• David Castel,

  Affiliations Université Paris-Sud, Gustave Roussy, CNRS UMR 8203 "Vectorologie et Thérapeutiques Anticancéreuses", Villejuif, France, Département de Cancérologie de l'Enfant et de l'Adolescent, Gustave Roussy, Villejuif, France

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• Felice Giangaspero,

  Affiliations Department of Radiology, Oncology and Anatomo-Pathology, Sapienza University, Roma, Italy, IRCCS Neuromed, Pozzilli, Isernia, Italy

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• Leila Chimelli,

  Affiliation Departamento de Patologia, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brazil

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• Pascale Varlet,

  Affiliations Département de Neuropathologie, Hôpital Sainte-Anne, Paris, France, Université Sorbonne Paris Cité, Paris, France

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• Stefan Rutkowski,

  Affiliation Department of Paediatric Hematology and Oncology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany

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• Didier Frappaz,

  Affiliation Institut d'Hématologie-Oncologie Pédiatrique, Lyon, France

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• Maura Massimino,

  Affiliation Paediatric Unit, Fondazione Istituto Di Ricovero e Cura a Carattere Scientifico, Istituto Nazionale dei Tumori, Milano, Italy

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• Richard Grundy,

  Affiliation The Children's Brain Tumour Research Centre, University of Nottingham, Nottingham, United Kingdom

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• Jacques Grill ,

  * E-mail: jacques.grill@gustaveroussy.fr

  Affiliations Université Paris-Sud, Gustave Roussy, CNRS UMR 8203 "Vectorologie et Thérapeutiques Anticancéreuses", Villejuif, France, Département de Cancérologie de l'Enfant et de l'Adolescent, Gustave Roussy, Villejuif, France

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•  [ ... ],
• on behalf of the SIOP Ependymoma Biology Working Group BIOMECA (BIOlogical Markers for Ependymomas in Children and Adolescents)

  ¶Membership of the BIOMECA working group is provided in the Acknowledgements.

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