CTRP3 is a novel biomarker for diabetic retinopathy and inhibits HGHL-induced VCAM-1 expression in an AMPK-dependent manner

Zheyi Yan; Jianli Zhao; Lu Gan; Yanqing Zhang; Rui Guo; Xiaoming Cao; Wayne Bond Lau; Xin Ma; Yajing Wang

doi:10.1371/journal.pone.0178253

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Peer-reviewed

Research Article

CTRP3 is a novel biomarker for diabetic retinopathy and inhibits HGHL-induced VCAM-1 expression in an AMPK-dependent manner

Zheyi Yan,

Affiliations Department of Ophthalmology, The First Affiliated Hospital, Shanxi Medical University, Taiyuan, Shanxi, China, Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA, United States of America
⨯
Jianli Zhao,

Affiliations Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA, United States of America, Department of Anesthesiology, The First Affiliated Hospital, Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Lu Gan,

Affiliations Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA, United States of America, Department of Physiology, Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Yanqing Zhang,

Affiliations Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA, United States of America, Department of Anesthesiology, The First Affiliated Hospital, Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Rui Guo,

Affiliations Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA, United States of America, Department of Physiology, Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Xiaoming Cao,

Affiliation Department of Orthopedics, The Second Affiliated Hospital, Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Wayne Bond Lau,

Affiliation Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA, United States of America
⨯
Xin Ma,

Affiliations Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA, United States of America, Department of Physiology, Shanxi Medical University, Taiyuan, Shanxi, China
⨯
Yajing Wang

* E-mail: yajing.wang@jefferson.edu

Affiliations Department of Emergency Medicine, Thomas Jefferson University, Philadelphia, PA, United States of America, Department of Physiology, Shanxi Medical University, Taiyuan, Shanxi, China

http://orcid.org/0000-0002-6358-6948

⨯

CTRP3 is a novel biomarker for diabetic retinopathy and inhibits HGHL-induced VCAM-1 expression in an AMPK-dependent manner

Zheyi Yan,
Jianli Zhao,
Lu Gan,
Yanqing Zhang,
Rui Guo,
Xiaoming Cao,
Wayne Bond Lau,
Xin Ma,
Yajing Wang

Published: June 20, 2017
https://doi.org/10.1371/journal.pone.0178253

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Diabetes mellitus
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Diabetic retinopathy
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Cell migration
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Lipoproteins
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