Controlled delivery of tauroursodeoxycholic acid from biodegradable microspheres slows retinal degeneration and vision loss in P23H rats

• Laura Fernández-Sánchez ,

  Contributed equally to this work with: Laura Fernández-Sánchez, Irene Bravo-Osuna

  ¶‡ These authors are first authors on this work.

  Affiliation Department of Physiology, Genetics and Microbiology, University of Alicante, Alicante, Spain

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• Irene Bravo-Osuna ,

  Contributed equally to this work with: Laura Fernández-Sánchez, Irene Bravo-Osuna

  ¶‡ These authors are first authors on this work.

  Affiliation Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Complutense University of Madrid, Madrid, Spain

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• Pedro Lax,

  Affiliation Department of Physiology, Genetics and Microbiology, University of Alicante, Alicante, Spain

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• Alicia Arranz-Romera,

  Affiliation Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Complutense University of Madrid, Madrid, Spain

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• Victoria Maneu,

  Affiliation Department of Optics, Pharmacology and Anatomy, University of Alicante, Alicante, Spain

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• Sergio Esteban-Pérez,

  Affiliation Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Complutense University of Madrid, Madrid, Spain

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• Isabel Pinilla,

  Affiliations Department of Ophthalmology, Lozano Blesa University Hospital, Zaragoza, Spain, Aragon Institute for Health Research (IIS Aragon), Zaragoza, Spain

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• María del Mar Puebla-González,

  Affiliation Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Complutense University of Madrid, Madrid, Spain

  ⨯
• Rocío Herrero-Vanrell ,

  * E-mail: cuenca@ua.es (NS); rociohv@ucm.es (RHV)

  Affiliations Department of Pharmacy and Pharmaceutical Technology, Faculty of Pharmacy, Complutense University of Madrid, Madrid, Spain, Sanitary Research Institute of the San Carlos Clinical Hospital (IdISSC), Madrid, Spain, Industrial Pharmacy Institute, Complutense University of Madrid, Madrid, Spain

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• Nicolás Cuenca

  * E-mail: cuenca@ua.es (NS); rociohv@ucm.es (RHV)

  Affiliations Department of Physiology, Genetics and Microbiology, University of Alicante, Alicante, Spain, Institute Ramón Margalef, University of Alicante, Alicante, Spain

  http://orcid.org/0000-0002-6767-5710

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