Electronic cigarette aerosols suppress cellular antioxidant defenses and induce significant oxidative DNA damage

• Vengatesh Ganapathy,

  Affiliation Department of Otorhinolaryngology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

  ⨯
• Jimmy Manyanga,

  Affiliations Department of Otorhinolaryngology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

  ⨯
• Lacy Brame,

  Affiliation Department of Otorhinolaryngology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

  ⨯
• Dehra McGuire,

  Affiliation Department of Otorhinolaryngology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

  ⨯
• Balaji Sadhasivam,

  Affiliation Department of Otorhinolaryngology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

  ⨯
• Evan Floyd,

  Affiliation Department of Occupational and Environmental Health, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

  ⨯
• David A. Rubenstein,

  Affiliation Department of Biomedical Engineering, Stony Brook University, New York, New York, United States of America

  ⨯
• Ilangovan Ramachandran,

  Affiliation Department of Endocrinology, Dr. ALM Post Graduate Institute of Basic Medical Sciences, University of Madras, Taramani Campus, Chennai, Tamil Nadu, India

  ⨯
• Theodore Wagener,

  Affiliations Department of Pediatrics, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Oklahoma Tobacco Research Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, The Peggy and Charles Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

  ⨯
• Lurdes Queimado

  * E-mail: lurdes-queimado@ouhsc.edu

  Affiliations Department of Otorhinolaryngology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Department of Cell Biology, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Department of Pediatrics, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, Oklahoma Tobacco Research Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America, The Peggy and Charles Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States of America

  http://orcid.org/0000-0002-1106-4873

  ⨯