Genetic micro-epidemiology of malaria in Papua Indonesia: Extensive P. vivax diversity and a distinct subpopulation of asymptomatic P. falciparum infections

Zuleima Pava; Rintis Noviyanti; Irene Handayuni; Hidayat Trimarsanto; Leily Trianty; Faustina H. Burdam; Enny Kenangalem; Retno A. S. Utami; Yusrifar K. Tirta; Farah Coutrier; Jeanne R. Poespoprodjo; Ric N. Price; Jutta Marfurt; Sarah Auburn

doi:10.1371/journal.pone.0177445

Loading metrics

Open Access

Peer-reviewed

Research Article

Genetic micro-epidemiology of malaria in Papua Indonesia: Extensive P. vivax diversity and a distinct subpopulation of asymptomatic P. falciparum infections

Zuleima Pava,

Affiliation Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia
⨯
Rintis Noviyanti,

Affiliation Malaria Pathogenesis Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia
⨯
Irene Handayuni,

Affiliation Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia
⨯
Hidayat Trimarsanto,

Affiliations Bioinformatics Laboratory, Eijkman Institute for Molecular Biology, Jakarta, Indonesia, Agency for Assessment and Application of Technology, Jakarta, Indonesia
⨯
Leily Trianty,

Affiliation Malaria Pathogenesis Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia
⨯
Faustina H. Burdam,

Affiliations Mimika District Health Authority, Timika, Papua, Indonesia, Timika Malaria Research Programme, Papuan Health and Community Development Foundation, Timika, Papua, Indonesia, Pediatric Research Office, Department of Child Health, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia
⨯
Enny Kenangalem,

Affiliations Mimika District Health Authority, Timika, Papua, Indonesia, Timika Malaria Research Programme, Papuan Health and Community Development Foundation, Timika, Papua, Indonesia
⨯
Retno A. S. Utami,

Affiliation Malaria Pathogenesis Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia
⨯
Yusrifar K. Tirta,

Affiliation Malaria Pathogenesis Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia
⨯
Farah Coutrier,

Affiliation Malaria Pathogenesis Unit, Eijkman Institute for Molecular Biology, Jakarta, Indonesia
⨯
Jeanne R. Poespoprodjo,

Affiliations Mimika District Health Authority, Timika, Papua, Indonesia, Timika Malaria Research Programme, Papuan Health and Community Development Foundation, Timika, Papua, Indonesia, Pediatric Research Office, Department of Child Health, Faculty of Medicine, Universitas Gadjah Mada, Yogyakarta, Indonesia
⨯
Ric N. Price,

Affiliations Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia, Centre for Tropical Medicine, Nuffield Department of Clinical Medicine, University of Oxford, Oxford, United Kingdom
⨯
Jutta Marfurt,

Affiliation Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia
⨯
Sarah Auburn

* E-mail: sarah.auburn@menzies.edu.au

Affiliation Global and Tropical Health Division, Menzies School of Health Research, Charles Darwin University, Darwin, Northern Territory, Australia

http://orcid.org/0000-0002-4638-536X

⨯

Genetic micro-epidemiology of malaria in Papua Indonesia: Extensive P. vivax diversity and a distinct subpopulation of asymptomatic P. falciparum infections

Zuleima Pava,
Rintis Noviyanti,
Irene Handayuni,
Hidayat Trimarsanto,
Leily Trianty,
Faustina H. Burdam,
Enny Kenangalem,
Retno A. S. Utami,
Yusrifar K. Tirta,
Farah Coutrier

Published: May 12, 2017
https://doi.org/10.1371/journal.pone.0177445

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Plasmodium
Is the Subject Area "Plasmodium" applicable to this article?

Thanks for your feedback.
Malaria
Is the Subject Area "Malaria" applicable to this article?

Thanks for your feedback.
Population genetics
Is the Subject Area "Population genetics" applicable to this article?

Thanks for your feedback.
Islands
Is the Subject Area "Islands" applicable to this article?

Thanks for your feedback.
Parasitic diseases
Is the Subject Area "Parasitic diseases" applicable to this article?

Thanks for your feedback.
Computer software
Is the Subject Area "Computer software" applicable to this article?

Thanks for your feedback.
Genotyping
Is the Subject Area "Genotyping" applicable to this article?

Thanks for your feedback.
Indonesia
Is the Subject Area "Indonesia" applicable to this article?

Thanks for your feedback.