Efficacy and safety at 24 weeks of daily clinical use of tofacitinib in patients with rheumatoid arthritis

Naoki Iwamoto; Sosuke Tsuji; Ayuko Takatani; Toshimasa Shimizu; Shoichi Fukui; Masataka Umeda; Ayako Nishino; Yoshiro Horai; Tomohiro Koga; Shin-ya Kawashiri; Toshiyuki Aramaki; Kunihiro Ichinose; Yasuko Hirai; Mami Tamai; Hideki Nakamura; Kaoru Terada; Tomoki Origuchi; Katsumi Eguchi; Yukitaka Ueki; Atsushi Kawakami

doi:10.1371/journal.pone.0177057

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Open Access

Peer-reviewed

Research Article

Efficacy and safety at 24 weeks of daily clinical use of tofacitinib in patients with rheumatoid arthritis

Naoki Iwamoto ,

* E-mail: naoki-iwa@nagasaki-u.ac.jp

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan

http://orcid.org/0000-0002-2197-0757

⨯
Sosuke Tsuji,

Affiliation Department of Rheumatology, Sasebo Chuo Hospital, Sasebo, Japan
⨯
Ayuko Takatani,

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Toshimasa Shimizu,

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Shoichi Fukui,

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Masataka Umeda,

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Ayako Nishino,

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Yoshiro Horai,

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Tomohiro Koga,

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Shin-ya Kawashiri,

Affiliation Departments of Community Medicine, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Toshiyuki Aramaki,

Affiliation Department of Rheumatology, Sasebo Chuo Hospital, Sasebo, Japan
⨯
Kunihiro Ichinose,

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Yasuko Hirai,

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Mami Tamai,

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Hideki Nakamura,

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Kaoru Terada,

Affiliation Department of Rheumatology, Sasebo Chuo Hospital, Sasebo, Japan
⨯
Tomoki Origuchi,

Affiliation Department of Physical Therapy, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
Katsumi Eguchi,

Affiliation Department of Rheumatology, Sasebo Chuo Hospital, Sasebo, Japan
⨯
Yukitaka Ueki,

Affiliation Department of Rheumatology, Sasebo Chuo Hospital, Sasebo, Japan
⨯
[ ... ],
Atsushi Kawakami

Affiliation Department of Immunology and Rheumatology, Unit of Advanced Preventive Medical Sciences, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan
⨯
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Efficacy and safety at 24 weeks of daily clinical use of tofacitinib in patients with rheumatoid arthritis

Naoki Iwamoto,
Sosuke Tsuji,
Ayuko Takatani,
Toshimasa Shimizu,
Shoichi Fukui,
Masataka Umeda,
Ayako Nishino,
Yoshiro Horai,
Tomohiro Koga,
Shin-ya Kawashiri

Published: May 4, 2017
https://doi.org/10.1371/journal.pone.0177057

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