Development of prostate specific membrane antigen targeted ultrasound microbubbles using bioorthogonal chemistry

Aimen Zlitni; Melissa Yin; Nancy Janzen; Samit Chatterjee; Ala Lisok; Kathleen L. Gabrielson; Sridhar Nimmagadda; Martin G. Pomper; F. Stuart Foster; John F. Valliant

doi:10.1371/journal.pone.0176958

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Open Access

Peer-reviewed

Research Article

Development of prostate specific membrane antigen targeted ultrasound microbubbles using bioorthogonal chemistry

Aimen Zlitni,

Current address: Department of Radiology, Stanford University, Stanford, California, United States of America.

Affiliation Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario, Canada
⨯
Melissa Yin,

Affiliation Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
⨯
Nancy Janzen,

Affiliation Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario, Canada
⨯
Samit Chatterjee,

Affiliation Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Ala Lisok,

Affiliation Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Kathleen L. Gabrielson,

Affiliation Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Sridhar Nimmagadda,

Affiliation Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
Martin G. Pomper,

Affiliation Russell H. Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, Maryland, United States of America
⨯
F. Stuart Foster ,

* E-mail: valliant@mcmaster.ca (JFV); stuart@sri.utoronto.ca (FSF)

Affiliation Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada
⨯
John F. Valliant

* E-mail: valliant@mcmaster.ca (JFV); stuart@sri.utoronto.ca (FSF)

Affiliations Department of Chemistry and Chemical Biology, McMaster University, Hamilton, Ontario, Canada, Centre for Probe Development and Commercialization, Hamilton, Ontario, Canada

http://orcid.org/0000-0002-1461-552X

⨯

Development of prostate specific membrane antigen targeted ultrasound microbubbles using bioorthogonal chemistry

Aimen Zlitni,
Melissa Yin,
Nancy Janzen,
Samit Chatterjee,
Ala Lisok,
Kathleen L. Gabrielson,
Sridhar Nimmagadda,
Martin G. Pomper,
F. Stuart Foster,
John F. Valliant

Published: May 4, 2017
https://doi.org/10.1371/journal.pone.0176958

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Cancers and neoplasms
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Cell binding
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Matrix-assisted laser desorption ionization time-of-flight mass spectrometry
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