Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca2+]i overload and NF-κB activation

Nadia A. Rivero-Segura; Edgar Flores-Soto; Selene García de la Cadena; Isabel Coronado-Mares; Juan C. Gomez-Verjan; Diana G. Ferreira; Erika Alejandra Cabrera-Reyes; Luísa V. Lopes; Lourdes Massieu; Marco Cerbón

doi:10.1371/journal.pone.0176910

Loading metrics

Open Access

Peer-reviewed

Research Article

Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca²⁺]i overload and NF-κB activation

Nadia A. Rivero-Segura,

Affiliation Unidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México (UNAM), Ciudad de México, México
⨯
Edgar Flores-Soto,

Affiliation Facultad de Medicina, Dpto. de Farmacología, Universidad Nacional Autónoma de México (UNAM), Ciudad de México, México
⨯
Selene García de la Cadena,

Affiliation División de Neurociencias, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México (UNAM), Ciudad de México, México
⨯
Isabel Coronado-Mares,

Affiliation Unidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México (UNAM), Ciudad de México, México
⨯
Juan C. Gomez-Verjan,

Affiliation Departamento de Investigación Básica, Instituto Nacional de Geriatría, Ciudad de México, México
⨯
Diana G. Ferreira,

Affiliation Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Lisboa, Portugal
⨯
Erika Alejandra Cabrera-Reyes,

Affiliation Unidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México (UNAM), Ciudad de México, México
⨯
Luísa V. Lopes,

Affiliation Instituto de Medicina Molecular, Faculdade de Medicina de Lisboa, Universidade de Lisboa, Lisboa, Portugal
⨯
Lourdes Massieu,

Affiliation División de Neurociencias, Instituto de Fisiología Celular, Universidad Nacional Autónoma de México (UNAM), Ciudad de México, México
⨯
Marco Cerbón

* E-mail: mcerbon85@yahoo.com.mx

Affiliation Unidad de Investigación en Reproducción Humana, Instituto Nacional de Perinatología-Facultad de Química, Universidad Nacional Autónoma de México (UNAM), Ciudad de México, México

http://orcid.org/0000-0002-2464-2732

⨯

Prolactin-induced neuroprotection against glutamate excitotoxicity is mediated by the reduction of [Ca²⁺]i overload and NF-κB activation

Nadia A. Rivero-Segura,
Edgar Flores-Soto,
Selene García de la Cadena,
Isabel Coronado-Mares,
Juan C. Gomez-Verjan,
Diana G. Ferreira,
Erika Alejandra Cabrera-Reyes,
Luísa V. Lopes,
Lourdes Massieu,
Marco Cerbón

Published: May 5, 2017
https://doi.org/10.1371/journal.pone.0176910

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Transcription factors
Is the Subject Area "Transcription factors" applicable to this article?

Thanks for your feedback.
Neurons
Is the Subject Area "Neurons" applicable to this article?

Thanks for your feedback.
Apoptosis
Is the Subject Area "Apoptosis" applicable to this article?

Thanks for your feedback.
Hippocampus
Is the Subject Area "Hippocampus" applicable to this article?

Thanks for your feedback.
Mitochondria
Is the Subject Area "Mitochondria" applicable to this article?

Thanks for your feedback.
Neuroprotectives
Is the Subject Area "Neuroprotectives" applicable to this article?

Thanks for your feedback.
MTT assay
Is the Subject Area "MTT assay" applicable to this article?

Thanks for your feedback.
Nuclear staining
Is the Subject Area "Nuclear staining" applicable to this article?

Thanks for your feedback.