Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β

Dequina A. Nicholas; Kangling Zhang; Christopher Hung; Shane Glasgow; Aruni Wilson Aruni; Juli Unternaehrer; Kimberly J. Payne; William H. R. Langridge; Marino De Leon

doi:10.1371/journal.pone.0176793

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Research Article

Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β

Dequina A. Nicholas,

Affiliations Center for Health Disparities and Molecular Medicine, Loma Linda University School of Medicine, Loma Linda, California, United States of America, Division of Biochemistry, Department of Basic Sciences, Loma Linda University School Medicine, Loma Linda, California, United States of America
⨯
Kangling Zhang,

Affiliation Department of Pharmacology and Toxicology, University of Texas Medical Branch, Galveston, Texas, United States of America
⨯
Christopher Hung,

Affiliations Center for Health Disparities and Molecular Medicine, Loma Linda University School of Medicine, Loma Linda, California, United States of America, Division of Biochemistry, Department of Basic Sciences, Loma Linda University School Medicine, Loma Linda, California, United States of America
⨯
Shane Glasgow,

Affiliations Center for Health Disparities and Molecular Medicine, Loma Linda University School of Medicine, Loma Linda, California, United States of America, Division of Biochemistry, Department of Basic Sciences, Loma Linda University School Medicine, Loma Linda, California, United States of America
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Aruni Wilson Aruni,

Affiliation Department of Basic Sciences, Division of Microbiology and Molecular Genetics, Loma Linda University School Medicine, Loma Linda, California, United States of America
⨯
Juli Unternaehrer,

Affiliations Center for Health Disparities and Molecular Medicine, Loma Linda University School of Medicine, Loma Linda, California, United States of America, Division of Biochemistry, Department of Basic Sciences, Loma Linda University School Medicine, Loma Linda, California, United States of America
⨯
Kimberly J. Payne,

Affiliations Center for Health Disparities and Molecular Medicine, Loma Linda University School of Medicine, Loma Linda, California, United States of America, Department of Anatomy and Physiology, Loma Linda University School Medicine, Loma Linda, California, United States of America
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William H. R. Langridge,

Affiliations Center for Health Disparities and Molecular Medicine, Loma Linda University School of Medicine, Loma Linda, California, United States of America, Division of Biochemistry, Department of Basic Sciences, Loma Linda University School Medicine, Loma Linda, California, United States of America
⨯
Marino De Leon

* E-mail: madeleon@llu.edu

Affiliations Center for Health Disparities and Molecular Medicine, Loma Linda University School of Medicine, Loma Linda, California, United States of America, Department of Basic Sciences, Division of Physiology, Loma Linda University School Medicine, Loma Linda, California, United States of America

http://orcid.org/0000-0001-6576-785X

⨯

Palmitic acid is a toll-like receptor 4 ligand that induces human dendritic cell secretion of IL-1β

Dequina A. Nicholas,
Kangling Zhang,
Christopher Hung,
Shane Glasgow,
Aruni Wilson Aruni,
Juli Unternaehrer,
Kimberly J. Payne,
William H. R. Langridge,
Marino De Leon

Published: May 2, 2017
https://doi.org/10.1371/journal.pone.0176793

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