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Open Access
Peer-reviewed
Research Article
Social defeat stress causes depression-like behavior with metabolite changes in the prefrontal cortex of rats
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Yi-Yun Liu ,
Contributed equally to this work with: Yi-Yun Liu, Xin-Yu Zhou, Li-Ning Yang, Hai-Yang Wang
Affiliations Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China
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Xin-Yu Zhou ,
Contributed equally to this work with: Yi-Yun Liu, Xin-Yu Zhou, Li-Ning Yang, Hai-Yang Wang
Affiliations Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China
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Li-Ning Yang ,
Contributed equally to this work with: Yi-Yun Liu, Xin-Yu Zhou, Li-Ning Yang, Hai-Yang Wang
Affiliations Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China
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Hai-Yang Wang ,
Contributed equally to this work with: Yi-Yun Liu, Xin-Yu Zhou, Li-Ning Yang, Hai-Yang Wang
Affiliations Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China, School of Public Health and Management, Chongqing Medical University, Chongqing, China
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Yu-Qing Zhang,
Affiliations Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China
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Jun-Cai Pu,
Affiliations Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China
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Lan-Xiang Liu,
Affiliations Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China
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Si-Wen Gui,
Affiliations Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China
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Li Zeng,
Affiliations Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China
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Jian-Jun Chen,
Affiliations Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China
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Chan-Juan Zhou,
Affiliations Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China
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Peng Xie
* E-mail: xiepeng@cqmu.edu.cn
Affiliations Department of Neurology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China, Chongqing Key Laboratory of Neurobiology, Chongqing Medical University, Chongqing, China, Institute of Neuroscience and the Collaborative Innovation Center for Brain Science, Chongqing Medical University, Chongqing, China
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Social defeat stress causes depression-like behavior with metabolite changes in the prefrontal cortex of rats
- Yi-Yun Liu,
- Xin-Yu Zhou,
- Li-Ning Yang,
- Hai-Yang Wang,
- Yu-Qing Zhang,
- Jun-Cai Pu,
- Lan-Xiang Liu,
- Si-Wen Gui,
- Li Zeng,
- Jian-Jun Chen
- Published: April 28, 2017
- https://doi.org/10.1371/journal.pone.0176725