Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation

Eric C. Sorenson; Raya Khanin; Zubin M. Bamboat; Michael J. Cavnar; Teresa S. Kim; Eran Sadot; Shan Zeng; Jonathan B. Greer; Adrian M. Seifert; Noah A. Cohen; Megan H. Crawley; Benjamin L. Green; David S. Klimstra; Ronald P. DeMatteo

doi:10.1371/journal.pone.0176562

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Open Access

Peer-reviewed

Research Article

Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation

Eric C. Sorenson,

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Raya Khanin,

Affiliation Department of Computational Biology and Bioinformatics Core, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Zubin M. Bamboat,

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Michael J. Cavnar,

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Teresa S. Kim,

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Eran Sadot,

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Shan Zeng,

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Jonathan B. Greer,

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Adrian M. Seifert,

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Noah A. Cohen,

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Megan H. Crawley,

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Benjamin L. Green,

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
David S. Klimstra,

Affiliation Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯
Ronald P. DeMatteo

* E-mail: dematter@mskcc.org

Affiliation Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York, United States of America
⨯

Genome and transcriptome profiling of fibrolamellar hepatocellular carcinoma demonstrates p53 and IGF2BP1 dysregulation

Eric C. Sorenson,
Raya Khanin,
Zubin M. Bamboat,
Michael J. Cavnar,
Teresa S. Kim,
Eran Sadot,
Shan Zeng,
Jonathan B. Greer,
Adrian M. Seifert,
Noah A. Cohen

Published: May 9, 2017
https://doi.org/10.1371/journal.pone.0176562

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