Pyridoxal phosphate synthases PdxS/PdxT are required for Actinobacillus pleuropneumoniae viability, stress tolerance and virulence

Fang Xie; Gang Li; Yalei Wang; Yanhe Zhang; Long Zhou; Chengcheng Wang; Shuanghong Liu; Siguo Liu; Chunlai Wang

doi:10.1371/journal.pone.0176374

Loading metrics

Open Access

Peer-reviewed

Research Article

Pyridoxal phosphate synthases PdxS/PdxT are required for Actinobacillus pleuropneumoniae viability, stress tolerance and virulence

Fang Xie,

Affiliation State Key Laboratory of Veterinary Biotechnology, Division of Bacterial Diseases, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People’s Republic of China
⨯
Gang Li,

Affiliation State Key Laboratory of Veterinary Biotechnology, Division of Bacterial Diseases, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People’s Republic of China
⨯
Yalei Wang,

Affiliation Shanghai Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Shanghai, People’s Republic of China
⨯
Yanhe Zhang,

Affiliation State Key Laboratory of Veterinary Biotechnology, Division of Bacterial Diseases, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People’s Republic of China
⨯
Long Zhou,

Affiliation State Key Laboratory of Veterinary Biotechnology, Division of Bacterial Diseases, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People’s Republic of China
⨯
Chengcheng Wang,

Affiliation State Key Laboratory of Veterinary Biotechnology, Division of Bacterial Diseases, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People’s Republic of China
⨯
Shuanghong Liu,

Affiliation State Key Laboratory of Veterinary Biotechnology, Division of Bacterial Diseases, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People’s Republic of China
⨯
Siguo Liu,

Affiliation State Key Laboratory of Veterinary Biotechnology, Division of Bacterial Diseases, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People’s Republic of China
⨯
Chunlai Wang

* E-mail: chunlai.w@hvri.ac.cn

Affiliation State Key Laboratory of Veterinary Biotechnology, Division of Bacterial Diseases, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Harbin, People’s Republic of China
⨯

Pyridoxal phosphate synthases PdxS/PdxT are required for Actinobacillus pleuropneumoniae viability, stress tolerance and virulence

Fang Xie,
Gang Li,
Yalei Wang,
Yanhe Zhang,
Long Zhou,
Chengcheng Wang,
Shuanghong Liu,
Siguo Liu,
Chunlai Wang

Published: April 27, 2017
https://doi.org/10.1371/journal.pone.0176374

Reader Comments (0)

Post a new comment on this article

Subject Areas
?

For more information about PLOS Subject Areas, click here.
We want your feedback. Do these Subject Areas make sense for this article? Click the target next to the incorrect Subject Area and let us know. Thanks for your help!

Biosynthesis
Is the Subject Area "Biosynthesis" applicable to this article?

Thanks for your feedback.
Mutant strains
Is the Subject Area "Mutant strains" applicable to this article?

Thanks for your feedback.
Glutamine
Is the Subject Area "Glutamine" applicable to this article?

Thanks for your feedback.
Polymerase chain reaction
Is the Subject Area "Polymerase chain reaction" applicable to this article?

Thanks for your feedback.
Mouse models
Is the Subject Area "Mouse models" applicable to this article?

Thanks for your feedback.
Oxidative stress
Is the Subject Area "Oxidative stress" applicable to this article?

Thanks for your feedback.
Osmotic shock
Is the Subject Area "Osmotic shock" applicable to this article?

Thanks for your feedback.
Plasmid construction
Is the Subject Area "Plasmid construction" applicable to this article?

Thanks for your feedback.