Imaging mass spectrometry identifies prognostic ganglioside species in rodent intracranial transplants of glioma and medulloblastoma

Leonardo Ermini; Elena Morganti; Alexander Post; Behzad Yeganeh; Isabella Caniggia; Michael Leadley; Claudia C. Faria; James T. Rutka; Martin Post

doi:10.1371/journal.pone.0176254

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Peer-reviewed

Research Article

Imaging mass spectrometry identifies prognostic ganglioside species in rodent intracranial transplants of glioma and medulloblastoma

Leonardo Ermini,

Affiliation Program in Physiology and Experimental Medicine, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario, Canada
⨯
Elena Morganti,

Affiliation Program in Physiology and Experimental Medicine, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario, Canada
⨯
Alexander Post,

Affiliation Program in Physiology and Experimental Medicine, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario, Canada
⨯
Behzad Yeganeh,

Affiliation Program in Physiology and Experimental Medicine, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario, Canada
⨯
Isabella Caniggia,

Affiliations The Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, Institute of Medical Science, University of Toronto, Ontario, Canada, Department of Physiology, University of Toronto, Ontario, Canada
⨯
Michael Leadley,

Affiliation Program in Physiology and Experimental Medicine, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario, Canada
⨯
Claudia C. Faria,

Affiliations Division of Neurosurgery, Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, Ontario, Canada, Instituto de Medicina Molecular, Faculdade de Medicina, Universidade de Lisboa, Lisbon, Portugal
⨯
James T. Rutka,

Affiliation Division of Neurosurgery, Arthur and Sonia Labatt Brain Tumour Research Centre, Hospital for Sick Children, Toronto, Ontario, Canada
⨯
Martin Post

* E-mail: martin.post@sickkids.ca

Affiliations Program in Physiology and Experimental Medicine, Peter Gilgan Centre for Research and Learning, Hospital for Sick Children, Toronto, Ontario, Canada, Institute of Medical Science, University of Toronto, Ontario, Canada, Department of Physiology, University of Toronto, Ontario, Canada
⨯

Imaging mass spectrometry identifies prognostic ganglioside species in rodent intracranial transplants of glioma and medulloblastoma

Leonardo Ermini,
Elena Morganti,
Alexander Post,
Behzad Yeganeh,
Isabella Caniggia,
Michael Leadley,
Claudia C. Faria,
James T. Rutka,
Martin Post

Published: May 2, 2017
https://doi.org/10.1371/journal.pone.0176254

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Sphingolipids
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Glioma
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Medulloblastoma
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Mass spectra
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Matrix-assisted laser desorption ionization mass spectrometry
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