Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish

Michael J. Carvan III; Thomas A. Kalluvila; Rebekah H. Klingler; Jeremy K. Larson; Matthew Pickens; Francisco X. Mora-Zamorano; Victoria P. Connaughton; Ingrid Sadler-Riggleman; Daniel Beck; Michael K. Skinner

doi:10.1371/journal.pone.0176155

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Peer-reviewed

Research Article

Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish

Michael J. Carvan III ,

Contributed equally to this work with: Michael J. Carvan III, Thomas A. Kalluvila

* E-mail: carvanmj@uwm.edu

Affiliations School of Freshwater Sciences, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America, Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America
⨯
Thomas A. Kalluvila ,

Contributed equally to this work with: Michael J. Carvan III, Thomas A. Kalluvila

Affiliations School of Freshwater Sciences, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America, Zilber School of Public Health, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America
⨯
Rebekah H. Klingler,

Affiliation School of Freshwater Sciences, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America
⨯
Jeremy K. Larson,

Affiliation School of Freshwater Sciences, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America
⨯
Matthew Pickens,

Affiliation School of Freshwater Sciences, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America
⨯
Francisco X. Mora-Zamorano,

Affiliation School of Freshwater Sciences, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin, United States of America
⨯
Victoria P. Connaughton,

Affiliation Department of Biology, American University,Washington, DC, United States of America
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Ingrid Sadler-Riggleman,

Affiliation Center for Reproductive Biology, School of Biological Sciences, Washington State University, Pullman, WA, United States of America
⨯
Daniel Beck,

Affiliation Center for Reproductive Biology, School of Biological Sciences, Washington State University, Pullman, WA, United States of America
⨯
Michael K. Skinner

Affiliation Center for Reproductive Biology, School of Biological Sciences, Washington State University, Pullman, WA, United States of America
⨯

Mercury-induced epigenetic transgenerational inheritance of abnormal neurobehavior is correlated with sperm epimutations in zebrafish

Michael J. Carvan III,
Thomas A. Kalluvila,
Rebekah H. Klingler,
Jeremy K. Larson,
Matthew Pickens,
Francisco X. Mora-Zamorano,
Victoria P. Connaughton,
Ingrid Sadler-Riggleman,
Daniel Beck,
Michael K. Skinner

Published: May 2, 2017
https://doi.org/10.1371/journal.pone.0176155

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