Phosphatidylcholine-specific phospholipase C inhibition down- regulates CXCR4 expression and interferes with proliferation, invasion and glycolysis in glioma cells

• Laura Mercurio ,

  Contributed equally to this work with: Laura Mercurio, Serena Cecchetti

  Affiliation Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy

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• Serena Cecchetti ,

  Contributed equally to this work with: Laura Mercurio, Serena Cecchetti

  * E-mail: egidio.iorio@iss.it (EI); serena.cecchetti@iss.it (SC)

  Affiliation Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy

  ⨯
• Alessandro Ricci,

  Affiliation Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy

  ⨯
• Aurora Pacella,

  Affiliation Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy

  ⨯
• Giovanni Cigliana,

  Affiliation Clinical Pathology Laboratories, Department of Research, Advanced Diagnostics, and Technological Innovation, Translational Research Area, Regina Elena National Cancer Institute, Rome, Italy

  ⨯
• Giuseppina Bozzuto,

  Affiliation Department of Technology and Health, Istituto Superiore di Sanità, Rome, Italy

  ⨯
• Franca Podo,

  Affiliation Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy

  ⨯
• Egidio Iorio ,

  * E-mail: egidio.iorio@iss.it (EI); serena.cecchetti@iss.it (SC)

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy

  http://orcid.org/0000-0001-6673-3838

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• Giulia Carpinelli

  ¶‡ These authors also contributed equally to this work.

  Affiliation Department of Cell Biology and Neurosciences, Istituto Superiore di Sanità, Rome, Italy

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