TGFβ/Smad3 regulates proliferation and apoptosis through IRS-1 inhibition in colon cancer cells

• Katie L. Bailey,

  Affiliation Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

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• Ekta Agarwal,

  Affiliations Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Nebraska, United States of America, Wistar Institute, Philadelphia, Pennsylvania

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• Sanjib Chowdhury,

  Affiliation Section of Gastroenterology, Department of Medicine, Boston University Medical Center, Boston, Massachusetts, United States of America

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• Jiangtao Luo,

  Affiliation Department of Biostatistics, College of Public Health, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

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• Michael G. Brattain †,

  † Deceased.

  Affiliations Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, United States of America, Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Nebraska, United States of America

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• Jennifer D. Black,

  Affiliation Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

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• Jing Wang

  * E-mail: jjwang@unmc.edu

  Affiliations Eppley Institute for Research in Cancer and Allied Diseases, University of Nebraska Medical Center, Omaha, Nebraska, United States of America, Department of Biochemistry and Molecular Biology, University of Nebraska Medical Center, Nebraska, United States of America, Department of Genetics, Cell Biology and Anatomy, University of Nebraska Medical Center, Omaha, Nebraska, United States of America

  http://orcid.org/0000-0002-6821-9266

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